ENGLISH

Viral Proteases and Antiviral Protease Inhibitor Therapy: Proteases in Biology and Disease

By Kuo-Chen Chou , Dong-Qing Wei , Qi-Shi Du (auth.) , Uwe Lendeckel , Nigel M. Hooper (eds.)

Book information

Publisher
Springer Netherlands
Year
2009
ISBN
904812347X, 9789048123476, 9789048123483
DOI
10.1007/978-90-481-2348-3
Language
english
Format
PDF
Filesize
5 MB (4759222 bytes)
Series
Proteases in Biology and Disease 8
Edition
1
Pages
132\139
Library
duansci.com
Time added
2010-05-17 00:23:50
Biomedicine general; Virology; Medicinal Chemistry

Description

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most important pathogenic viruses, responsible for severe diseases: AIDS, SARS, Hepatitis, Cytomegalovirus, T-cell lymphotropic virus, Picornavirus. This book focuses specifically on the viral proteases, crucial prerequisites for viral entry into cells and viral replication. Viral proteases represent an important pharmaceutical target. The current stage of protease inhibitor development and therapy are summarised and discussed by experts in the field. This volume represents a timely and valuable continuation of the Proteases in Biology and Disease series. The reader will learn the potential for proteases as targets for effective anti-virals. This book will be a valuable source of information on viral proteases and provoke further research in this important field.

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