Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives

Description

Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain-axis in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain-axis modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others. This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders. Contents Contributors 1 Overview of microbiota gut-brain-axis • Ruchika Sharma, Kuttiappan Anitha, Neeraj Mishra and Anoop Kumar 2 Role of microbiota-gut-brain axis in Alzheimer’s disease and possible interventions • Rohini Pujari, Shreya Sharma and Shvetank Bhatt 3 Role of microbiota gutebrain axis in Parkinson’s disease • Rani Mansuri, Meenakshi Dhanawat, Shital Patel, Garima and Anupama Diwan 4 Role of microbiota-gut-brain axis in Huntington’s disease and possible interventions • Sachin Kumar and Laxmi Yadav 5 Crosstalk between gut-brain axis and brain components along with associated neurological disorders • Priya Bindal, Swati Kaushal, Charan Singh and Arti Singh 6 Role of microbiome-gut-brain axis in autism spectrum disorder • Jagdish Chand, Neha Patel and Pragyanshu Khare 7 Role of microbiota-gut-brain axis in autoimmunity and multiple sclerosis • Yogesh Mishra, Dipan Maity and Ravinder K. Kaundal 8 Negative impact of stress on gut-brain axis • Monalisa Das, Amit K. Goyal and Sanjib Patra 9 Role of microbiota-gut-brain axis in epilepsy and possible interventions • Inklisan Patel and Awanish Mishra 10 Role of microbiota-gut-brain axis in migraine and possible interventions • Sarjana Raikwar and Sanjay K. Jain 11 Role of microbiota gut brain axis in stroke and its possible intervention • Pankaj Madhukar Totwad, Monika Deore, Manoj Goyal, Ashima Thakur, Charan Singh and Jayant Kumar 12 Role of microbiota-gut-brain axis in brain infections and possible interventions • Poonam Sharma, Bhupesh Sharma, Kamlesh Kumar Vishwakarma, A. Raghu Rama Setty, Parth Sandeep, Neerupma Dhiman and Sandeep Arora 13 Role of microbiome gut-brain axis in brain disorders • Smriti Parashar, Devesh U. Kapoor, Rupesh K. Gautam and Ajit Kumar Thakur 14 Role of gut microbiota in neuropsychiatric and neurological disorders • Tushar Mishra, Vikrant Rahi, Ashwini Kamble and Ravinder K. Kaundal 15 Role of microbiota-gut-brain axis in obesity on cognitive functions • Hema Gandhi, Sandeep Arora and Maryam Sarwat 16 Role of microbiota-gut-brain axis on neurotransmitter modulation • Kuttiappan Anitha, Shvetank Bhatt, Chikatipalli Radhika and Parameshwar Ravula 17 Role of gut virome and mycobiome in neurological disorders • Aparna Chaudhary 18 Role of nutraceuticals in neurological disease • Ashish Garg, Sweta Garg, Vishal Singh, Gopal Rai, Prakash Pandey and Neeraj Mishra 19 Future prospective of microbiome-gut brain axis for treatment of CNS disorders • Ramdas Mane, Saurabh Kashid, Farhan Mazahir and Awesh Kumar Yadav Index