Oral Mucosal Immunity and Microbiome
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The first International Conference on Oral Mucosal Immunity and Microbiome (OMIM) aimed to highlight cutting-edge basic and translational research from an oral immunological and microbiological perspective. Oral diseases with a microbial etiology are the most prevalent chronic diseases of humans. Whilst not life-threatening, they can significantly compromise quality of life, are associated with increased risk for certain systemic diseases, and pose heavy financial burdens to national health systems. Hence, periodontal and peri-implant diseases, dental caries, root canal infections and mucosal infections are significant global public health problems. In this book global experts summarize and discuss the latest progress made in oral mucosal immunity and the oral microbiome. Target audience is basic and/or translational researchers with expertise in host immunity and microbiome research, and interest in oral health and disease. This volume provides a much needed quantum leap in the field, by joining forces to address gaps at the oral mucosal immunity-microbiome cross-talk. Front Matter ....Pages i-xii Advances in Oral Mucosal Immunity and the Microbiome (Georgios N. Belibasakis, George Hajishengallis)....Pages 1-9 Trained Innate Immunity and Its Implications for Mucosal Immunity and Inflammation (George Hajishengallis, Xiaofei Li, Ioannis Mitroulis, Triantafyllos Chavakis)....Pages 11-26 Signaling Systems in Oral Bacteria (Daniel P. Miller, Richard J. Lamont)....Pages 27-43 Origin of Th17 Cells in Type 2 Diabetes-Potentiated Periodontal Disease (Barbara S. Nikolajczyk, Dolphus R. Dawson III)....Pages 45-54 Gingival Epithelial Cell Recognition of Lipopolysaccharide (Nutthapong Kantrong, Thao T. To, Richard P. Darveau)....Pages 55-67 The Relationship of Candida albicans with the Oral Bacterial Microbiome in Health and Disease (Martinna Bertolini, Anna Dongari-Bagtzoglou)....Pages 69-78 A Potential Role of Phospholipase 2 Group IIA (PLA2-IIA) in P. gingivalis-Induced Oral Dysbiosis (Octavio A. Gonzalez, Vanessa Euzebio-Alves, Yelena Alimova, Ahmad Al-Attar, J. L. Ebersole)....Pages 79-95 Helicobacter spp. in Experimental Models of Colitis (Christoph Mueller, Cheong K. C. Kwong Chung, Martin R. Faderl, Jennifer Brasseit, Daniel Zysset)....Pages 97-105 T Helper 17 Cells as Pathogenic Drivers of Periodontitis (Nicolas Dutzan, Loreto Abusleme)....Pages 107-117 Candida–Bacterial Biofilms and Host–Microbe Interactions in Oral Diseases (Thais de Cássia Negrini, Hyun Koo, Rodrigo Alex Arthur)....Pages 119-141 Comparative Analysis of Gene Expression Patterns for Oral Epithelium-Related Functions with Aging (J. L. Ebersole, L. Orraca, M. J. Novak, S. Kirakodu, J. Gonzalez-Martinez, O. A. Gonzalez)....Pages 143-163 Neutrophil Interaction with Emerging Oral Pathogens: A Novel View of the Disease Paradigm (Irina Miralda, Aruna Vashishta, Silvia M. Uriarte)....Pages 165-178 Biologically Defined or Biologically Informed Traits Are More Heritable Than Clinically Defined Ones: The Case of Oral and Dental Phenotypes (Cary S. Agler, Kevin Moss, Kamaira H. Philips, Julie T. Marchesan, Miguel Simancas-Pallares, James D. Beck et al.)....Pages 179-189
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