ENGLISH

Antisense Therapeutics

By Sudhir Agrawal

Book information

Publisher
Humana Press
Year
1996
ISBN
9780896033054, 0896033058
LCC
RM666.A564 A585 1996
Google Books ID
vyzIz4tG3SEC
Open Library ID
OL967017M
Language
english
Format
PDF
Filesize
22 MB (23276384 bytes)
Series
Methods in Molecular Medicine
Edition
1st
Pages
270\270
Topic
Medicine Therapy
Library
mexmat
Scanned
no
Time added
2009-07-20 03:45:11

Description

Leading researchers offer an authoritative survey and analysis of the latest findings on the rapid development of antisense oligonucleotides therapeutic and their application in various in vivo model systems. The book's high-profile contributors provide timely accounts of their state-of-the-art strategies, discussing such topics as the synthesis and purification of oligonucleotides, their selection for a particular gene target, different methods of administration, and the use of various cell lines and cell culture systems. They also examine questions of cellular uptake, in vitro biological activity, in vivo biological activity, the pharmacology and pharmacokinetics of oligonucleotides, and the application of oligonucleotides to the central nervous system.

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