PET-CT: A Case-Based Approach

Description

This book presents original case studies performed on dedicated PET-CT devices and showcases common and uncommon cancers and the latest PET-CT applications for neurological, pediatric, and cardiovascular disorders. This authoritative book, now in its Second Edition, presents correlative three-dimensional cross-sectional PET and CT images that highlight pathological findings. Each case example is accompanied by a concise explanation of the patient history and interpretation of the PET-CT study. "Pearls and pitfalls" and insightful discussions are included to assist in the understanding of pathology, diagnosis, and imaging approaches. The book also discusses pathophysiology and technical artifacts and summarizes the advantages and limitations of using this technology in the clinical setting. PET-CT: A Case-Based Approach, Second Edition, is a valuable resource for nuclear medicine practitioners, radiologists, and residents, as well as referring clinicians interested in learning more about how this imaging modality can be applied in their patient populations.    Peter S. Conti is a Professor of Radiology and the Director of the PET Imaging Science Center at the University of Southern California, and is a Fellow of both the American College of Radiology and American College of Nuclear Physicians. He is a pioneer in the development of the clinical applications of PET and PET-CT. Dedication Preface Acknowledgments Contents Contributors 1: Normal Patterns and Artifacts Bone Marrow Hyperplasia Metal Implants Pacemaker Artifact Epidural Stimulator Artifact Vascular Uptake [Aorta] and Bilateral Hip Joint with Peripheral Uptake: Inflammatory Degenerative Changes Post-RFA Assessment Lesions Post-RFA of Hepatic Lesion Photopenia (Absent Uptake) on PET Images on the Left Correlating with Low Attenuation Region on CT Subclinical Aspiration Postradiation Changes in the Mid Spine with Low Bone Mineral Density on CT and Photopenia (Absent Uptake) on PET Thymic Hyperplasia Post Chemotherapy Dextrocardia Muscular Uptake Variations on PET/CT Scan Radiation Myositis Weight Lifting Sit-Ups Prior to Injection Tense, Cervical, and Intercostal Muscular Uptake PET Uptake Secondary to Inflammatory Changes Post Subcutaneous Injections Gluteal Subcutaneous Uptake, Postinjection Soft Tissue Changes on CT Thigh Subcutaneous Uptake, Postinjection Soft Tissue Changes on CT Attenuation Correction Artifact Vertebroplasty Artifact, Increase Uptake on AC Images (Left) with no Uptake on NAC Images (Right) 2: Lung Neoplasms References 3: Breast Neoplasms References 4: Esophageal and Gastric Neoplasms Suggested Reading 5: Hepatobiliary, Pancreas, Adrenal, Melanoma, and GIST Suggested Reading 6: Colon Neoplasms Suggested Reading 7: Gynecologic Neoplasms: Cervical, Ovarian, Vulvar, Uterine, and Endometrial Cancer Cervical Cancer Ovarian Cancer Endometrial/Uterine Cancer Vulvar Cancer References 8: Urologic Neoplasms: Prostate, Bladder, and Renal Cell Carcinoma Prostate Cancer Bladder Cancer Renal Cell Carcinoma References 9: Lymphoma References 10: Musculoskeletal Neoplasms Suggested Reading 11: F-18 Fluoride Bone Scintigraphy Prostate Cancer Breast Cancer Lung Cancer Additional Benign Findings References 12: Neuroradiology: Neoplasms and Epilepsy References 13: Dementia Suggested Reading 14: Pediatric Imaging Suggested Reading 15: Myocardial Viability FDG Viability Scintigraphy Introduction Overview Technique [18F]-FDG Cardiac Viability Imaging Protocol Scheduling Considerations Patient Preparation Radiopharmaceutical Dosage Clinical Imaging Procedure Artifacts Associated with PET-CT Myocardial Perfusion Scintigraphy Misregistration of PET and CT Transmission Data Breast Attenuation Artifact Attenuation Attributed to Large Region of Interest Noncardiac Findings Suggested Reading 16: Granulomatous Diseases References 17: Newer Tracers 18F-AV-45 and 18F-FDG 64Cu-ATSM (64Cu-ATSM: Copper (II)-Diacetyl-­Bis(N4-Methylthiosemicarbazone) and 18F-FDG) 18F-MISO (18F-Fluoromisonidazole) F-18 FLT Index