Pathophysiology of Disease: An Introduction to Clinical Medicine

Description

A full-color case-based review of the essentials of pathophysiology covering all major organs and systems More than 130 case studies with Q&A The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 132 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. The accessible presentation features high-quality full-color illustrations, and numerous tables and diagrams. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. HERE ARE SOME OF THE MANY UPDATES AND ADDITIONS:• Twelve additional case studies, bringing the total to 132, one for each of the clinical entities discussed in the book’s 24 chapters• More than 2/3 of the chapters are enhanced and refreshed by the input of new contributors• Totally revised chapter on neoplasia• New chapter sections on urticaria, spinocerebellar ataxia, idiopathic pulmonary fibrosis, and spondyloarthropathies• New tables summarizing adverse prognostic signs in acute pancreatitis, genetic syndromes associated with pancreatic cancer, and causes of end-stage renal disease• New diagnosis and etiologic classification of diabetes mellitus, and review of mechanisms of newest pharmacologic agents for its treatment• Updates on fine-needle aspiration biopsy of thyroid nodules, and thyroid disorders in pregnancy• Updated references throughout the book Cover......Page 2 Title Page......Page 4 Copyright Page......Page 6 Contents......Page 9 Authors......Page 12 Preface......Page 23 1. Introduction......Page 31 2. Genetic Disease......Page 33 3. Disorders of the Immune System......Page 91 4. Infectious Diseases......Page 157 5. Neoplasia......Page 211 6. Blood Disorders......Page 313 7. Nervous System Disorders......Page 383 8. Diseases of the Skin......Page 487 9. Pulmonary Disease......Page 558 10. Cardiovascular Disorders: Heart Disease......Page 658 11. Cardiovascular Disorders: Vascular Disease......Page 742 12. Disorders of the Adrenal Medulla......Page 800 13. Gastrointestinal Disease......Page 828 14. Liver Disease......Page 935 15. Disorders of the Exocrine Pancreas......Page 1032 16. Renal Disease......Page 1097 17. Disorders of the Parathyroids & Calcium and Phosphorus Metabolism......Page 1154 18. Disorders of the Endocrine Pancreas......Page 1234 19. Disorders of the Hypothalamus & Pituitary Gland......Page 1295 20. Thyroid Disease......Page 1353 21. Disorders of the Adrenal Cortex......Page 1408 22. Disorders of the Female Reproductive Tract......Page 1483 23. Disorders of the Male Reproductive Tract......Page 1542 24. Inf lammatory Rheumatic Diseases......Page 1595 25. Case Study Answers......Page 1642 Index......Page 1765