ENGLISH

The Thalassaemia Syndromes, Fourth Edition

By D.J. Weatherall , J.B. Clegg(auth.)

Book information

Publisher
Blackwell Science Ltd
Year
2001
ISBN
9780865426641, 9780470696705
DOI
10.1002/9780470696705
Language
english
Format
PDF
Filesize
8 MB (8416453 bytes)
Pages
848\848
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00

Description

In the new edition of this successful and authoritative book, the thalassaemias are reviewed in detail with respect to their clinical features, cellular pathology, molecular genetics, prevention and treatment. It is aimed at specialists in haematology in the laboratory or clinical setting, particularly in areas where thalassaemia is common either in the native population or in immigrant communities.The fourth edition has been both updated and re-organized. Three new chapters have been added on the link between alpha-thalassaemia and mental retardation, on avoidance and population control and on global epidemiology. Considerable emphasis is placed on molecular pathology reflecting the huge burst of information to have come out of this field in the last few years. Content: Chapter 1 Historical Perspectives: The Many and Diverse Routes to Our Current Understanding of the Thalassaemias (pages 1–62): Chapter 2 Human Haemoglobin (pages 63–120): Chapter 3 Thalassaemia: Classification, Genetics and Relationship to Other Inherited Disorders of Haemoglobin (pages 121–132): Chapter 4 The Molecular Pathology of the Thalassaemias (pages 133–191): Chapter 5 The Pathophysiology of the Thalassaemias (pages 192–236): Chapter 6 Distribution and Population Genetics of the Thalassaemias (pages 237–284): Chapter 7 The ? Thalassaemias (pages 285–356): Chapter 8 The ?? and Related Thalassaemias (pages 357–392): Chapter 9 The ? and ?? Thalassaemias in Association with Structural Haemoglobin Variants (pages 393–449): Chapter 10 Hereditary Persistence of Fetal Haemoglobin (pages 450–483): Chapter 11 The ? Thalassaemias and their Interactions with Structural Haemoglobin Variants (pages 484–525): Chapter 12 ? Thalassaemia with Mental Retardation or Myelodysplasia (pages 526–549): Chapter 13 Thalassaemia Intermedia (pages 550–594): Chapter 14 Avoidance and Population Control (pages 595–629): Chapter 15 Management and Prognosis (pages 630–685): Chapter 16 The Laboratory Diagnosis of the Thalassaemias (pages 686–723):

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