Pulmonary Function Testing: Principles and Practice

Description

This book serves as a unique, comprehensive resource for physicians and scientists training in pulmonary medicine and learning about pulmonary function testing. Pulmonary function testing and the physiological principles that underlie it are often poorly understood by medical students, residents, fellows and graduate students training in the medical sciences. One reason is that students tend to get overwhelmed by the basic mathematical descriptions that explain the working of the respiratory system and the principles of pulmonary function testing. Another reason is that too many approaches focus on the math without explaining the clinical relevance of these principles and the laboratory testing that enables us to measure the very lung function that these principles are describing. This book answers that need by providing a series of chapters that guide the reader in a natural order of learning about the respiratory system. In particular, after a general overview of the structure-function design of the lung and the history of pulmonary function testing, authors begin with the drive to breathe, and then follow the pathway of air as it is drawn into the lung, undergoes gas exchange, and is then exhaled back out again. Each chapter focuses on the key principles and corresponding pulmonary function tests that explain each step in this pathway. Each chapter is written by at least two experts, one with expertise in the underlying physiology, and the other with expertise in the clinical testing and application of pulmonary function testing in practice. Many figures and tables highlight key points, and multiple case studies in each section provide specific examples of the clinical application of each pulmonary function test. This is an ideal guide to pulmonary function tests for practicing pulmonologists, residents, fellows, and medical students. Front Matter ....Pages i-xiv Introduction to the Structure and Function of the Lung (Jeff Thiboutot, Bruce R. Thompson, Robert H. Brown)....Pages 1-13 The History of Pulmonary Function Testing (Tianshi David Wu, Meredith C. McCormack, Wayne Mitzner)....Pages 15-42 Breathing In: The Determinants of Lung Volume (Charles G. Irvin, Jack Wanger)....Pages 43-60 Distribution of Air: Ventilation Distribution and Heterogeneity (Gregory King, Sylvia Verbanck)....Pages 61-76 Gas Exchange (Brian L. Graham, Neil MacIntyre, Yuh Chin Huang)....Pages 77-101 Breathing Out: Forced Exhalation, Airflow Limitation (James A. Stockley, Brendan G. Cooper)....Pages 103-125 Breathing In and Out: Airway Resistance (David A. Kaminsky, Jason H. T. Bates)....Pages 127-150 Initiating the Breath: The Drive to Breathe, Muscle Pump (Jeremy Richards, Matthew J. Fogarty, Gary C. Sieck, Richard M. Schwartzstein)....Pages 151-170 Measurement of Airway Responsiveness (Teal S. Hallstrand, John D. Brannan, Krystelle Godbout, Louis-Philippe Boulet)....Pages 171-195 Field Exercise Testing: 6-Minute Walk and Shuttle Walk Tests (Annemarie L. Lee, Theresa Harvey-Dunstan, Sally Singh, Anne E. Holland)....Pages 197-217 Integrating the Whole: Cardiopulmonary Exercise Testing (J. Alberto Neder, Andrew R. Tomlinson, Tony G. Babb, Denis E. O’Donnell)....Pages 219-248 Special Considerations for Pediatric Patients (Graham L. Hall, Daniel J. Weiner)....Pages 249-269 Reference Equations for Pulmonary Function Tests (Bruce H. Culver, Sanja Stanojevic)....Pages 271-289 Management of and Quality Control in the Pulmonary Function Laboratory (Susan Blonshine, Jeffrey Haynes, Katrina Hynes)....Pages 291-311 Back Matter ....Pages 313-318