Management of Rare Adult Tumours

Description

Why a book dedicated to rare cancer management? Given the large variety of rare cancers,they take up a significant part of our daily practice. Therefore,we owe it to our patients with rare tumours that we use the knowledge gained in the treatment of the more common cancers to provide them with a better future. This knowledge comes from recent developments in molecular diagnostics, systemic treatments with new drugs and targeted therapies together with advanced technologies in the areas of radiology and radiation therapy. The authors have analyzed the literature and recommend treatments for rare cancers based on results from past studies.We hope that this book will be an aid to those treating rare cancer cases about which, up to now, little has been published, and will reassure our patients that they have not been forgotten. Yazid Belkacémi is Deputy Head of the Department of Radiation Oncology at the Centre Hospitalo-Universitaire Henri Mondor, Créteil, France. His clinical research interests include the management of breast and gynaecologic cancers, hematologic malignancies, rare tumour management and the development of new technologies in radiation oncology. His biology research topics include radiosensitivity markers in tumours and healthy tissues and combinations of targeted therapies and new drugs with ionising radiation. “As « rarity » is too often synonymous with isolation, it is hoped that this book will contribute to increasing and spreading the knowledge about rare tumours in order to better manage our patients with innovative approaches.“ René-Olivier Mirimanoff is Head of the Department of Radiation Oncology at the Centre Hospitalier Universitaire Vaudois (CHUV) and the University of Lausanne, Switzerland. He is also the founder of the Rare Cancer Network. (www.rarecancer.net). His main research interests are brain tumours and rare cancers. “Rare types of cancer should no longer be considered as orphan diseases.It is time now to gather solid data to guide our medical, radiation and surgical oncology colleagues towards the best possible decisions.“ Mahmut Ozsahin is Deputy Chairman of the Department of Radiation Oncology of the Centre Hospitalier Universitaire Vaudois/University Hospital of Lausanne, Switzerland. His main interests are head and neck cancer, colorectal cancer and haematological malignancies with a special interest in rare tumours in these sites. His biology research topics include radiosensitivity in healthy tissues and predictive assays in radiotherapy. “As no, or very little, prospective clinical research is carried out on rare tumours, it is important to gather and communicate our findings to improve the outcome of our patients.” Front Matter....Pages I-4 Front Matter....Pages 5-5 Germinal tumours of the central nervous system in adult patients....Pages 7-18 Atypical and malignant meningiomas....Pages 19-27 Primary central nervous system lymphoma....Pages 29-40 Treatment of Medulloblastoma in adults....Pages 41-44 Cerebellar Glioblastoma multiforme....Pages 45-50 Chordoma and chondrosarcoma of the skull base....Pages 51-56 Primary spinal epidural lymphoma....Pages 57-63 Front Matter....Pages 65-65 Esthesioneuroblastoma....Pages 67-72 Extranodal NK/T-cell lymphoma, nasal-type....Pages 73-85 Uncomon tumours of the nasopharynx....Pages 87-95 Uncommon tumours of the oral cavity and oropharynx....Pages 97-104 Rare malignant tumours of the larynx and hypopharynx....Pages 105-115 Primary Orbital Lymphoma....Pages 117-122 Primary MALT lymphoma of the salivary glands....Pages 123-126 Front Matter....Pages 127-127 Mucosal melanoma of the upper aero-digestive tract....Pages 129-135 Gastrointestinal stromal tumours....Pages 137-148 Small cell carcinomas of the gastrointestinal tract....Pages 149-157 Anorectal Melanoma....Pages 159-166 Primary adenocarcinoma of the anal canal....Pages 167-173 Anal margin tumours....Pages 175-182 Front Matter....Pages 127-127 Uncommon Hepatobiliary Tumours....Pages 183-194 Unusual pancreatic tumours....Pages 195-206 Front Matter....Pages 207-207 Rare tumours of the renal pelvis and ureter....Pages 209-213 Rare tumours of the urethra....Pages 215-224 Uncommon bladder cancers....Pages 225-233 Neuroendocrine small cell carcinoma of the prostate: A brief review of pathology, clinical characteristics and treatment guidelines....Pages 235-243 Uncommon tumours of the testis....Pages 245-253 Primary Testicular lymphoma....Pages 255-259 Human chorionic gonadotropin-producing seminoma....Pages 261-267 Front Matter....Pages 269-29 Rare Ovarian Cancers....Pages 271-278 Extraovarian primary peritoneal carcinoma....Pages 279-292 Uterine papillary serous carcinoma....Pages 293-299 Uterine sarcomas and rare endometrial carcinomas....Pages 301-306 Rare tumours of the uterine cervix....Pages 307-316 Tumours of the vagina and tumours of the vulva....Pages 317-327 Front Matter....Pages 329-329 Invasive breast cancer and ductal carcinoma in situ in young women....Pages 331-339 Tubular carcinoma of the breast....Pages 341-348 Adenoid Cystic Carcinoma of the Breast....Pages 349-352 Primary squamous cell carcinoma of the breast....Pages 353-356 Primary breast lymphoma....Pages 357-366 Front Matter....Pages 329-329 Phyllodes tumours of the breast....Pages 367-371 Primary Breast Sarcomas....Pages 373-378 Angiosarcoma of the breast....Pages 379-384 Male breast cancer....Pages 385-392 Front Matter....Pages 393-393 Primary uncommon tumours of the lung: lymphomas, sarcomas and melanomas....Pages 395-400 Thymoma and thymic carcinoma....Pages 401-413 Large Cell Neuroendocrine Carcinoma of the Lung....Pages 415-421 Neuroendocrine tumours of the lung....Pages 423-433 Pleural Mesothelioma....Pages 435-443 Bronchioloalveolar carcinoma and adenocarcinoma with bronchioloalveolar carcinoma features: a clinico-pathological spectrum....Pages 445-452 Primary adenoid cystic carcinoma of the trachea and bronchus....Pages 453-460 Tracheal Cancers....Pages 461-467 Front Matter....Pages 469-469 Unusual cutaneous malignancies: cutaneous adnexal tumours....Pages 471-477 Kaposi’s sarcoma....Pages 479-484 Dermatofibrosarcoma protuberans (DFSP)....Pages 485-490 Merkel cell carcinoma: A Challenge in Cancer Management....Pages 491-498 Langerhans cell histiocytosis (LCH)....Pages 499-512 Front Matter....Pages 513-513 Primary bone lymphoma (Osteolymphoma)....Pages 515-522 Erdheim-Chester disease....Pages 523-529 Solitary plasmacytoma....Pages 531-538 Front Matter....Pages 513-513 Neuroendocrine tumours....Pages 539-550