Diabetes and the Brain

Description

Diabetes, particularly type 2, has become increasingly more common around the world. Consequently, the effect of diabetes on the brain has achieved enormous public health importance. A surge in pre-clinical and clinical research on topics ranging from management of hyperglycemia in acute stroke to disturbances in insulin signaling in Alzheimer's disease has led to substantial progress in the field. Written by a panel of international experts, Diabetes and the Brain provides in depth reviews on the cerebral complications of diabetes, and offers introductory chapters on current insights on the pathophysiology and clinical management of diabetes, as well as neuropsychological assessment and dementia. This relevant and easily accessible book explains the cerebral complications of diabetes, with an update on diabetes for neurologists, psychiatrists, and mental health providers and researchers in general,and on stroke and dementia for those involved in research and clinical practice in diabetes. Front Matter....Pages i-xi Front Matter....Pages 1-1 Type 1 Diabetes....Pages 3-32 Type 2 Diabetes....Pages 33-53 Front Matter....Pages 55-55 Acute Ischemic Stroke....Pages 57-75 Neuropsychological Assessment....Pages 77-102 Clinical Evaluation and Treatment of Cognitive Dysfunction and Dementia....Pages 103-127 Front Matter....Pages 129-129 Hypoglycemia....Pages 131-157 Ketoacidosis and Hyperglycemic Hyperosmolar State....Pages 159-182 Stroke and Diabetes Mellitus....Pages 183-218 Hyperglycemia in Acute Stroke....Pages 219-247 Front Matter....Pages 249-249 Cognition in Children and Adolescents with Type 1 Diabetes....Pages 251-275 Cognition in Adults with Type 1 Diabetes....Pages 277-293 Cognition in Type 2 Diabetes or Pre-diabetic Stages....Pages 295-322 Type 2 Diabetes, Related Conditions, and Dementia....Pages 323-342 Diabetes and Depression....Pages 343-363 Central Nervous System Involvement in Diabetic Neuropathy....Pages 365-383 Front Matter....Pages 385-385 Animal Models....Pages 387-408 Pathobiology of Diabetic Encephalopathy in Animal Models....Pages 409-431 The Role of Insulin Resistance in Age-Related Cognitive Decline and Dementia....Pages 433-457 Back Matter....Pages 459-473