ENGLISH

Toxicity and Autophagy in Neurodegenerative Disorders

By José M. Fuentes (eds.)

Book information

Publisher
Springer International Publishing
Year
2015
ISBN
978-3-319-13938-8, 978-3-319-13939-5
DOI
10.1007/978-3-319-13939-5
Language
english
Format
PDF
Filesize
7 MB (6838997 bytes)
Series
Current Topics in Neurotoxicity 9
Edition
1
Pages
268\277
Time added
2015-07-18 18:00:00
Neurochemistry

Description

Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

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