ENGLISH

Antimicrobial Peptides: Discovery, Design and Novel Therapeutic Strategies

By Guangshun Wang

Book information

Publisher
Cab Intl
Year
2017
ISBN
1786390396, 978-1-78639-039-4, 978-1-78639-040-0, 178639040X, 978-1-78639-041-7
Language
english
Format
PDF
Filesize
9 MB (9317346 bytes)
Edition
2nd edition
Pages
268\288
Time added
2018-02-03 10:00:00
Antimicrobial Cationic Peptides;Anti-Infective AgeInnate;Drug Design;Antimikrobieller Wirkstoff;Pept

Description

Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide. Harnessing and creating AMPs synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. This new edition lays the foundations for studying AMPs, including a discovery timeline, terminology, nomenclature and classifications. It covers current advances in AMP research and examines state-of-the-art technologies such as bioinformatics, combinatorial libraries, high-throughput screening, database-guided identification, genomics and proteomics-based prediction, and structure-based design of AMPs. Thoroughly updated and revised, this second edition contains new content covering: defensins; cathelicidins; anti-MRSA, antifungal, antiviral, anticancer and antibiofilm strategies; combined treatments; adjuvants in vaccines; advances in AMP technologies that cover surface coating to prevent biofilm formation; nanofiber encapsulation technologies for delivery and sustained release; and understanding innate immunity and the basis for immune boosting to overcome obstacles in developing AMPs into therapeutic agents. Written and reviewed by a group of established investigators in the field, Antimicrobial Peptides is a valuable resource for postgraduate students, researchers, educators, and medical and industrial personnel

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