ENGLISH

Targeted Drug Strategies for Cancer and Inflammation

By Larry H. Matherly , Ndeye Diop-Bove (auth.) , Ann L. Jackman , Christopher P. Leamon (eds.)

Book information

Publisher
Springer-Verlag New York
Year
2011
ISBN
978-1-4419-8416-6, 978-1-4419-8417-3
DOI
10.1007/978-1-4419-8417-3
Language
english
Format
PDF
Filesize
4 MB (4447509 bytes)
Edition
1
Pages
254\262
Time added
2013-10-20 05:25:02
Cancer Research; Pharmacology/Toxicology

Description

The discoveries highlighted in this book parallel the emergence of innovative “molecular targeted” small molecules and monoclonal antibodies, i.e. agents that target proteins within highly activated signal transduction pathways that control proliferation. Many of the tumor-targeted strategies described within cross the boundaries between what’s considered to be “molecular targeted” versus conventional systemic therapy. However, the main theme of this volume is the folate receptor (FR), with much of the content focused on its basic biology and regulation as well as its exploitation for targeted therapy and diagnostic imaging.

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