ENGLISH

Early Diagnosis and Preventive Therapy in Parkinson’s Disease

By Dr. W. Poewe , F. Gerstenbrand , E. Karamat (auth.) , Prof. Dr. Horst Przuntek , Prof. Dr. Peter Riederer (eds.)

Book information

Publisher
Springer-Verlag Wien
Year
1989
ISBN
978-3-211-82080-3, 978-3-7091-8994-8
DOI
10.1007/978-3-7091-8994-8
Language
english
Format
PDF
Filesize
28 MB (29031687 bytes)
Series
Key Topics in Brain Research
Edition
1
Pages
447\438
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
generalNeurology; Internal Medicine; Neurosciences; Pharm

Description

At the time when "Parkinson's Disease" is diagnosed in a patient, roughly two thirds of dopaminergic neurons of substantia nigra are already degenerated. The onset of the disease must, therefore, be much earlier. This book deals with early diagnosis and early preventive treatment which may sustain the process underlying the disease. By use of psychometric, kinesiologic, physiologic, histologic, biochemical, endocrinologic, pharmacologic and imaging techniques, including positron-emission tomography and brain mapping, specialists tried to focus on new diagnostic criteria. New methods including psychometric evaluation, apparative measurement of movement, analysis of peripheral blood and urinary constituents have supplemented this approach. It has been agreed that early preventive therapy consists of low dosis of L-DOPA plus benserazide, L-deprenyl and dopaminergic agonists.

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