Ciba Foundation Symposium - Bacterial Episomes and Plasmids
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Volume 1 Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis. Volume 2Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data. This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored. Content: Chapter 1 Introduction: What are Episomes and Plasmids? (pages 4–11): W. HayesChapter 2 The Concept of Prophage (pages 12–31): Allan Campbell, Sankar Adhya and Karen KillenChapter 3 The Escherichia coli Sex Factor (pages 32–51): Neil Willetts and Paul BrodaChapter 4 Genetic Regulation of Early Functions in Bacteriophage ? (pages 52–64): Harvey EisenChapter 5 Control of Replication of Genetic Material in Bacteria (pages 65–80): R. H. PritchardChapter 6 Transferable Drug Resistance: The Nature of the Problem (pages 81–101): Tsutomu WatanabeChapter 7 Ecology and Epidemiology of Transferable Drug Resistance (pages 102–119): E. S. AndersonChapter 8 Sex Factor Activity of Drug?Resistance Factors (pages 120–135): Elinor Meynell and Naomi DattaChapter 9 Relationships Between Extrachromosomal Elements (pages 136–162): Stanley Falkow, Daniel K. Haapala and Richard P. SilverChapter 10 The Recombination of Colicinogenic Factors with Other Episomes and Plasmids (pages 163–178): Pierre FredericqChapter 11 Genetic Interactions of Penicillinase Plasmids in Staphylococcus aureus (pages 179–200): M. H. Richmond and Joan JohnstonChapter 12 Incompatibilities and Restrictions in Plasmid Transmission (pages 201–212): Werner ArberChapter 13 Veterinary Implications of Transfer Activity (pages 213–226): H. Williams SmithChapter 14 Medical Aspects of Transferable Drug Resistance (pages 243–257): Y. A. Chabbert, J. G. Baudens and D. H. BouanchaudChapter 14a General Discussion (pages 243–257): Chapter 15 Summary (pages 258–260): Professor S. E. Luria
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