ENGLISH

Strategies for Organic Drug Synthesis and Design, Second Edition

By Daniel Lednicer(auth.)

Book information

Year
2008
ISBN
9780470190395, 9780470399613
DOI
10.1002/9780470399613
Language
english
Format
PDF
Filesize
26 MB (27743551 bytes)
Pages
689\689
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00

Description

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.Content: Chapter 1 Prostaglandins, Peptidomimetic Compounds, and Retinoids (pages 1–41): Chapter 2 Drugs Based on a Substituted Benzene Ring (pages 43–88): Chapter 3 Indenes, Naphthalenes, and Other Polycyclic Aromatic Compounds (pages 89–117): Chapter 4 Steroids; Part 1: Estranes, Gonanes, and Androstanes (pages 119–159): Chapter 5 Steroids; Part 2: Compounds Related to Progesterone, Cortisone, and Cholesterol (pages 161–190): Chapter 6 Nonsteroidal Sex Hormones and Their Antagonists (pages 191–211): Chapter 7 Opioid Analgesics (pages 213–238): Chapter 8 Drugs Based on Five?Membered Heterocycles (pages 239–318): Chapter 9 Drugs Based on Six?Membered Heterocycles (pages 319–382): Chapter 10 Five?Membered Heterocycles Fused to a Benzene Ring (pages 383–427): Chapter 11 Six?Membered Heterocycles Fused to a Benzene Ring (pages 429–494): Chapter 12 Seven?Membered Heterocyclic Rings Fused to Benzene (pages 495–514): Chapter 13 Heterocycles Fused to Two Aromatic Rings (pages 515–544): Chapter 14 Beta Lactam Antibiotics (pages 545–575): Chapter 15 Heterocycles Fused to Other Heterocyclic Rings (pages 577–632):

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