Terpenoids: Recent Advances in Extraction, Biochemistry and Biotechnology

Description

Terpenoids are commercially important chemicals found in essential oils and other natural plant sources. They are used in solving issues that affect agricultural production, making them a key component of sustainable agronomy. Terpenoids: Recent Advances in Extraction, Biochemistry and Biotechnology provides information about the varied use of terpenoids in the control of pests, microbial diseases, ticks, and weeds. Chapters have prioritized terpenoids produced by plants, endophytic fungi, propolis, and geopropolis. The book also provides focused information about the functions of terpenoids in plants, as well as their biosynthetic pathways of production. The reference provides readers with a broad and diverse picture of the applications of terpenoids in plant safety, and creates an awareness of the possibilities for innovative biotechnological approaches for their extraction that make all the difference to agricultural production. Professionals and scholars involved in chemical technology, biotechnology and agriculture will benefit from the information provided in the book. It also serves as a comprehensive update for general readers interested in terpenoids and their current impact on the agricultural industry. Cover Title Copyright End User License Agreement Contents Preface ACKNOWLEDGEMENTS DEDICATION List of Contributors Biosynthesis of Terpenoids By Plants Akemi L. Niitsu1, Elesandro Bornhofen2 and Tábata Bergonci3,* INTRODUCTION Mevalonic Acid Pathway Methylerythritol Phosphate Pathway Isomerization of the C5 Building Blocks Geranyl Pyrophosphate Farnesyl Pyrophosphate Geranylgeranyl Pyrophosphate Cytokinin’s Biosynthesis CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Green Extraction Techniques to Obtain Bioactive Concentrates Rich in Terpenoids Ana Carolina de Aguiar1,*, Arthur Luiz Baião Dias1 and Juliane Viganó2 INTRODUCTION LOW-PRESSURE EXTRACTION METHODS Microwave-Assisted Extraction (MAE) Ultrasound-Assisted Extraction (UAE) HIGH-PRESSURE EXTRACTION METHODS Supercritical Fluid Extraction (SFE) Pressurized Liquid Extraction (PLE) Liquefied Petroleum Gas (LPG) Extraction CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Terpenoids Produced by Plant Endophytic Fungi from Brazil and their Biological Activities: A Review from January 2015 To June 2021 Lourivaldo Silva Santos1,*, Giselle Skelding Pinheiro Guilhon1, Railda Neyva Moreira Araujo2, Antonio José Cantanhede Filho3, Manoel Leão Lopes Junior4, Haroldo da Silva Ripardo Filho5 and Kiany Sirley Brandão Cavalcante3 INTRODUCTION Terpenoids Monoterpenoids Sesquiterpenoids Sesterterpenoids Meroterpenoids Triterpenoids CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Volatile Terpenoids in Myrtaceae Species: Chemical Structures and Applications Oberdan Oliveira Ferreira1,2, Celeste de Jesus Pereira Franco2, Angelo Antônio Barbosa de Moraes2, Giovanna Moraes Siqueira2, Lidiane Diniz Nascimento3, Márcia Moraes Cascaes2, Mozaniel Santana de Oliveira1,2,* and Eloisa Helena de Aguiar Andrade3 INTRODUCTION Myrtaceae Family and General Aspects Essential Oil of Myrtaceae Rich in Terpenoids APPLICATIONS Antioxidant Activity Anti-Inflammatory Activity Neuroprotective Activity Cytotoxicity Activity Anti-protozoan Activity Antidiabetic Activity Recent Advances in Phytotherapy CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Volatile Terpenoids of Annonaceae: Occurrence and Reported Activities Márcia M. Cascaes1,2,*, Giselle M. S. P. Guilhon1, Lidiane D. Nascimento2,3, Angelo A. B. de Moraes2, Sebastião G. Silva1, Jorddy Neves Cruz2, Oberdan O. Ferreira4, Mozaniel S. Oliveira2 and Eloisa H. A. Andrade1,2 INTRODUCTION CHEMICAL DIVERSITY OF VOLATILE TERPENOIDS BIOACTIVITY OF THE ESSENTIAL OILS FROM ANNONACEAE SPECIES Acetylcholinesterase Inhibition Antimicrobial Activities Anti-Inflammatory Activity Antiproliferative and Cytotoxic Activities Larvicidal Activity Trypanocidal and Antimalarial Activities Other Activities ANTIOXIDANT POTENTIAL CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Repellent Potential of Terpenoids Against Ticks Tássia L. Vale1, Isabella C. Sousa1, Caio P. Tavares1, Matheus N. Gomes1, Geovane F. Silva1, Jhone R. S. Costa1, Aldilene da Silva Lima, Claudia Q. Rocha and Livio Martins Costa-Júnior1 INTRODUCTION Terpenoids Repellent Against Ticks Bioassays to Evaluate Repellent Compounds Against Ticks Tick Climbing Bioassay Olfactometer Bioassay Petri Dish Bioassay Bioassay of the Falcon Tissue Flask Repellency Moving Object Bioassay Repellent Compound on Ticks of Medical Importance Repellent Compounds on Dogs’ Ticks Repellent Compounds on Livestock’s Ticks CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Use of Terpenoids to Control Helminths in Small Ruminants Dauana Mesquita-Sousa1, Victoria Miro2, Carolina R. Silva1, Juliana R. F. Pereira1, Livio M. Costa-Júnior1, Guillermo Virkel2 and Adrian Lifschitz2,* INTRODUCTION Mechanism of Action of the Anthelmintic Compound Neuromuscular System and Motility Control Terpenoids with Action in GABA The Action of the Terpenoids on Tubulin Structural Alterations Combination of Synthetic Anthelmintics and Terpenoids Influence of Pharmacological Properties of Monoterpenes on their Anthelmintic Effect In Vivo Anthelmintic Effect of Monoterpenes CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENT REFERENCES Terpenes Behavior in Soil Marcia M. Mauli1, Adriana M. Meneghetti2 and Lúcia H. P. Nóbrega3 INTRODUCTION Terpenoids Biosynthesis of IPP (Isopentyl Diphosphate) and DMAPP (Dimethylallyl Diphosphate) The Mevalonic Acid Pathway (MVA) Methylerithritol-Phosphate Pathway (MEP) Hemiterpenes C5 Monoterpenes C10 Sesquiterpenes C15 Diterpenes C20 Triterpenoids C30 Tetraterpenoids C40 Secondary Metabolites Allelochemicals Behavior in the Environment Allelochemicals Behavior in Soil Terpenes in Soil CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENT REFERENCES Potential Use of Terpenoids in Weed Management Mozaniel Santana de Oliveira1,*, Jordd Nevez Cruz1, Eloisa Helena de Aguiar Andrade1 and Antônio Pedro da Silva Souza Filho2 INTRODUCTION [Volatile Terpenoids] Volatile Terpenoids Monoterpenes with Phytotoxic Potential Sesquiterpenes with Phytotoxic Potential Diterpenes with Phytotoxic Potential CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGMENTS REFERENCES Applications of Natural Terpenoids as Food Additives Fernanda Wariss Figueiredo Bezerra1,*, Giselle Cristine Melo Aires1, Lucas Cantão Freitas1, Marielba de Los Angeles Rodriguez Salazar1, Rafael Henrique Holanda Pinto1, Jorddy Neves da Cruz2 and Raul Nunes de Carvalho Junior1 INTRODUCTION DIVERSITY AND CHARACTERISTICS OF TERPENOIDS IN FOOD SYSTEMS POSSIBLE APPLICATIONS OF THE TERPENOIDS AS FOOD ADDITIVES Colorants Flavoring Agent Anti-Oxidants Anti-Microbial Nutraceutical CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Potential Use of Terpenoids for Control of Insect Pests Murilo Fazolin1,*, Humberto Ribeiro Bizzo2 and André Fábio Medeiros Monteiro1 INTRODUCTION MECHANISMS OF INSECTICIDAL ACTION OF TERPENOIDS Binding of GABA (Gamma-Aminobutyric Acid) Neurotransmitter to Receptors Binding to the Nicotinic Acetylcholine Receptor Inhibition of Transient Receptor Potential (TRP) Channels Activity on Octopamine and Tyramine Receptors Inhibition of Detoxification Enzymes INSECTICIDE FORMULATIONS USING TERPENOIDS Synergistic Interactions Between Terpenoids for Insecticide Formulation Production of Blends From Synergistic Terpenoids Present in Essential Oils and Development of Commercial Products Essential Oil-Based Products with High Levels of Terpenoids Challenges to the Production of Commercial Insecticides Based on Essential Oils and Terpenoids Insect Resistance to Commercial Terpenoid-Based Insecticides CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENT REFERENCES Potential Antimicrobial Activities of Terpenoids Hamdy A. Shaaban1,* and Amr Farouk1 INTRODUCTION Antibacterial Activity Antiviral Effect Terpenoids and Essential Oils as Antimicrobial Agents in Food Preservation The Site of Influence of Terpenoids and Essential Oils Factors Affecting Antimicrobial Activity CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENT REFERENCES Terpenoids in Propolis and Geopropolis and Applications Jorddy Neves Cruz1,2,*, Mozaniel Santana de Oliveira2, Lindalva Maria de Meneses Costa Ferreira3, Daniel Santiago Pereira1, João Paulo de Holanda Neto4, Aline Carla de Medeiros5, Patrício Borges Maracajá6 and Antônio Pedro da Silva Souza Filho1 INTRODUCTION TERPENOIDS PRESENT IN PROPOLIS FROM APIS MELLIFERA BEES TERPENOIDS PRESENT IN PROPOLIS AND GEOPROPOLIS OF STINGLESS BEES RECENT APPLICATIONS OF PROPOLIS AND GEOPROPOLIS IN THE FOOD AND PHARMACEUTICAL INDUSTRIES CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Terpenoids and Biotechnology Jorddy Neves Cruz1,2,*, Fernanda Wariss Figueiredo Bezerra3, Renan Campos e Silva4, Mozaniel Santana de Oliveira1, Márcia Moraes Cascaes1, Jose de Arimateia Rodrigues do Rego5, Antônio Pedro da Silva Souza Filho2, Daniel Santiago Pereira2 and Eloisa Helena de Aguiar Andrade1 INTRODUCTION BIOTECHNOLOGY OF TERPENE PRODUCTION IN MICROORGANISMS PHARMACEUTICAL APPLICATIONS OF TERPENOIDS PRODUCED BY BIOTECHNOLOGICAL METHODS BIOTECHNOLOGICAL APPLICATIONS OF TERPENES CONCLUDING REMARKS CONSENT FOR PUBLICATION CONFLICT OF INTEREST ACKNOWLEDGEMENTS REFERENCES Subject Index Back Cover