Dynamic Light Scattering Spectroscopy of the Human Eye

Description

Blindness or serious vision impairment is one of the most feared disabilities known to humankind. A 2016 report compiled by the National Eye Institute (NEI) of the National Institutes of Health (NIH) and Prevent Blindness America states that although half of all blindness can be prevented, the number of people who suffer vision loss continues to increase.  The technique of dynamic light scattering (DLS) was developed by physicists in the late 1960s to early 1970s. DLS is now emerging as a potential ophthalmic tool, making possible studies of virtually every tissue and fluid comprising the eye, thus pushing the envelope for broader applications in ophthalmology. This book presents a comprehensive review of the application of light scattering in clinical use. It is the first of its kind, offering insight to how DLS can be applied to the human eye as well as animals. Chapters discuss DLS in neurological diseases, including protocols, informed consent, and patents.  Dynamic Light Scattering Spectroscopy of the Human Eye is a must-have resource for physicians, engineers, and physicists interested in the clinical application of DLS to diagnose and potentially treat medical conditions in a non-invasive, quantitative and novel way.  Preface Contents Chapter 1: Ocular Anatomy How Does the Eye Work? Chapter 2: Light Scattering Summary of Light Scattering in the Eye Cornea Lens Vitreous Retina Chapter 3: Dynamic Light Scattering (DLS) Spectroscopy Analysis Cumulant Method CONTIN Algorithm Further Reading Chapter 4: Animal Experiments Chapter 5: Human Studies Chapter 6: Neurologic Diseases: Protocol Introduction Type of Research Purpose and Objective of the Study Background of the Study Study Rationale Participant Selection Study Design/Method/Procedures Summary of Research Design Performance of Measurements General Side Effects Collection and Used of Data Analysis of Study Results Storage of Data Confidentiality of Data Risk/Benefit Assessment Adverse Events Benefits Participant Recruitment and Informed Consent Recruiting Length of Study Informed Consent/Assent Chapter 7: Neurologic Diseases: Informed Consent Introduction Terms of the Study Reproductive Information for Females Benefits/Outcome of Treatment Description of Procedure Cost Collection and Use of Data Confidentiality of Records Available Information Termination Participant Statement and Authorization Chapter 8: Patents: Apparatus for the Detection of Diabetes and Other Abnormalities Affecting the Lens of the Eye Related U.S. Patent Documents References Cited [Referenced by] U.S. Patent Documents Other References Parent Case Text Cross-reference to Related Applications Claims I Claim Description Field of the Invention Background of the Invention Summary of the Invention Brief Description of the Drawings Detailed Description of the Preferred Embodiment Chapter 9: Patents: Diabetes Detection Method #1 Related U.S. Patent Documents Other References Parent Case Text Cross-reference to Related Applications Claims I Claim Description Field of the Invention Background of the Invention Summary of the Invention Brief Description of the Drawings Detailed Description of the Method Chapter 10: Patents: Diabetes Detection Method #2 Related U.S. Patent Documents References Cited [Referenced by] U.S. Patent Documents Parent Case Text Cross-reference to Related Applications Claims Description Field of the Invention Background of the Invention Summary of the Invention Brief Description of the Drawings Detailed Description of the Method Chapter 11: Patents: Filed Patent Application—Apparatus and Method for the Detection of Dementia and Retinal Conditions Field of the Invention Background of the Invention Summary of the Invention Brief Description of the Drawings Detailed Description Claims Bibliography Index