ENGLISH

Dipeptidyl Aminopeptidases in Health and Disease

By Nathan Back , Irun R. Cohen , David Kritchevsky , Abel Lajtha , Ingrid De Meester , Anne-Marie Lambeir , Paul Proost , Simon Scharpé (auth.) , Rodolfo Paoletti (eds.)

Book information

Publisher
Springer US
Year
2004
ISBN
9780306477171, 9780306479205, 0306477173
DOI
10.1007/b105297
LCC
QR186.6.C42 I58 2002
Open Library ID
OL19060455M
Language
english
Format
PDF
Filesize
10 MB (10887035 bytes)
Series
Advances in Experimental Medicine and Biology 524
Edition
1
Pages
359\392
Time added
2011-06-04 13:46:07
generalImmunology; Pharmacy; Internal Medicine; Biochemis

Description

Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: - Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.

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