ENGLISH

The Integrin Interactome: Methods and Protocols

By Miguel Vicente-Manzanares

Book information

Publisher
Springer US;Humana
Year
2021
ISBN
9781071609613, 9781071609620
DOI
10.1007/978-1-0716-0962-0
Language
english
Format
PDF
Filesize
9 MB (9234739 bytes)
Series
Methods in Molecular Biology 2217
Edition
1st ed.
Pages
XIX, 315\314
Time added
2021-01-06 05:41:07
Life Sciences; Cell Biology

Description

This volume provides the most cutting edge technologies related to the study of integrin activation and the characterization of their vast interactomes. Chapters detail protocols on experimental approached to quantify focal adhesion parameters, integrin activation, and the lateral interaction of integrins with transmembrane binding partners. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Integrin Interactome: Methods and Protocols aims to give the reader a multi-scale journey from single bonds inside protein structures to the function of these crucial adhesion receptors at a whole organism level in physiology and pathology.

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