Arthropod Vector: Controller of Disease Transmission, Volume 2. Vector Saliva-Host Pathogen Interactions

Description

Arthropod Vector: Controller of Disease Transmission, Volume 2: Vector Saliva-Host Pathogen Interactions is built on topics initially raised at a related Keystone Symposium on Arthropod Vectors. Together with the separate, related Volume 1: Controller of Disease Transmission, this work presents a logical sequence of topic development that leads to regulatory considerations for advancing these and related concepts for developing novel control measures. The three themes of symbionts, vector immune defenses and arthropod saliva modulation of the host environment are central to the concept of determinants of vector competence that involves all aspects of vector-borne pathogen development within the arthropod that culminates in the successful transmission to the vertebrate host. These three areas are characterized at the present time by rapid achievement of significant, incremental insights, which advances our understanding for a wide variety of arthropod vector species, and this work is the first to extensively integrate these themes. Content: Front Matter,Copyright,List of Contributors,PrefaceEntitled to full textChapter 1 - Network of Cells and Mediators of Innate and Adaptive Cutaneous Immunity: Challenges for an Arthropod Vector, Pages 1-11, Esther von Stebut Chapter 2 - Vector Arthropods and Host Pain and Itch Responses, Pages 13-29, Stephen Wikel Chapter 3 - Arthropod Modulation of Wound Healing, Pages 31-50, Stephen Wikel Chapter 4 - Salivary Kratagonists: Scavengers of Host Physiological Effectors During Blood Feeding, Pages 51-63, John F. Andersen, José M.C. Ribeiro Chapter 5 - Basic and Translational Research on Sand Fly Saliva: Pharmacology, Biomarkers, and Vaccines, Pages 65-89, Waldionê de Castro, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Shaden Kamhawi, Jesus G. Valenzuela Chapter 6 - Unique Features of Vector-Transmitted Leishmaniasis and Their Relevance to Disease Transmission and Control, Pages 91-114, Tiago D. Serafim, Ranadhir Dey, Hira L. Nakhasi, Jesus G. Valenzuela, Shaden Kamhawi Chapter 7 - Early Immunological Responses Upon Tsetse Fly–Mediated Trypanosome Inoculation, Pages 115-132, Guy Caljon, Benoît Stijlemans, Carl De Trez, Jan Van Den Abbeele Chapter 8 - Mosquito Modulation of Arbovirus–Host Interactions, Pages 133-144, Stephen Higgs, Yan-Jang S. Huang, Dana L. Vanlandingham Chapter 9 - Tick Saliva: A Modulator of Host Defenses, Pages 145-168, Stephen Wikel Chapter 10 - Tick Saliva and Microbial Effector Molecules: Two Sides of the Same Coin, Pages 169-194, Dana K. Shaw, Erin E. McClure, Michail Kotsyfakis, Joao H.F. Pedra Chapter 11 - Tsetse Fly Saliva Proteins as Biomarkers of Vector Exposure, Pages 195-208, Jan Van Den Abbeele, Guy Caljon Chapter 12 - Epidemiological Applications of Assessing Mosquito Exposure in a Malaria-Endemic Area, Pages 209-229, Andre Sagna, Anne Poinsignon, Franck Remoue Chapter 13 - Ixodes Tick Saliva: A Potent Controller at the Skin Interface of Early Borrelia burgdorferi Sensu Lato Transmission, Pages 231-248, Sarah Bonnet, Nathalie Boulanger Chapter 14 - Translation of Saliva Proteins Into Tools to Prevent Vector-Borne Disease Transmission, Pages 249-300, Sukanya Narasimhan, Tyler R. Schleicher, Erol Fikrig Chapter 15 - Considerations for the Translation of Vector Biology Research, Pages 301-307, Adriana Costero-Saint Denis, Wolfgang W. Leitner, Tonu Wali, Randall Kincaid Index, Pages 309-315