ENGLISH

The Hippocampus: Neurotransmission and Plasticity in the Nervous System

By Philippe Taupin

Book information

Publisher
Nova Science Publishers
Year
2008
ISBN
9781600219146, 9781606927533, 1600219144
LCC
QP383.25 .T38 2007
Open Library ID
OL16716863M
Language
english
Format
PDF
Filesize
1 MB (1257285 bytes)
Pages
154\154
Topic
Medicine
Library
avaxhome.ws
Scanned
yes
Time added
2010-05-31 15:29:46

Description

The hippocampus , the Greek word for seahorse, is one of the most fascinating and intriguing regions of the mammalian brain. It is a bilateral incurved seahorse-shaped structure of the cerebral cortex. The hippocampus has a highly distinctive morphology. It is composed of two regions, the dentate gyrus (DG) and the Cornu Ammonis (CA). The nerve cells of the main layer of the DG and CA regions, the granule cells and pyramidal cells respectively, are organised in a tri-synaptic lamellaire circuit. The granule and pyramidal cells are glutamatergic excitatory. The granule cells elicit unique histological, biochemical, developmental, physio- and pathological features.The hippocampus is also an area of the brain that elicits a high degree of plasticity, like synaptic and phenotypic plasticity. It is also one of the few regions of the brain where neurogenesis, the generation of new nerve cells, occurs throughout adulthood. The hippocampus is involved in physio-and pathological processes, like learning and memory.

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