Immune Hematology

Description

This text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children. The book is divided into four sections, each of which focuses on a major autoimmune cytopenia. The first section features background, pathophysiology, presentation, evaluation, and treatment strategies for immune thrombocytopenia (ITP), the most common cause of antibody-mediated platelet destruction. The second section reviews common forms and treatment strategies for autoimmune hemolytic anemia (AIHA), including a chapter dedicated specifically to Evans Syndrome. The third section comprehensively reviews the pathophysiology, diagnosis and current management approaches to thrombotic thrombocytopenic purpura (TTP), a potentially life-threatening autoimmune syndrome. The book concludes with a final section on autoimmune neutropenia. Each section includes a review of common underlying systemic autoimmune conditions and immune deficiency syndromes that can accompany or cause autoimmune cytopenias. Written by experts in each content area, Immune Hematology: Diagnosis and Management of Autoimmune Cytopenias is a valuable resource for clinicians and professionals who treat patients afflicted with autoimmune cytopenias, including primary care providers, hematologist/oncologists, immunologists, among others. Front Matter ....Pages i-x Front Matter ....Pages 1-1 Background of Immune Thrombocytopenia (Kristina M. Haley)....Pages 3-15 Pathophysiology of Immune Thrombocytopenia (Taylor Olmsted Kim)....Pages 17-33 Presentation and Evaluation of Immune Thrombocytopenia (Vicky R. Breakey)....Pages 35-44 The Treatment of Immune Thrombocytopenia (Kandace L. Gollomp, Michele P. Lambert)....Pages 45-80 Front Matter ....Pages 81-81 Background, Presentation and Pathophysiology of Autoimmune Hemolytic Anemia (Shawki Qasim)....Pages 83-102 Treatment of Autoimmune Hemolytic Anemia (Omar Niss, Russell E. Ware)....Pages 103-123 Evans Syndrome: Background, Clinical Presentation, Pathophysiology, and Management (Amanda B. Grimes)....Pages 125-150 Front Matter ....Pages 151-151 Background and Presentation of Thrombotic Thrombocytopenic Purpura (Clay Cohen)....Pages 153-169 Pathophysiology of Thrombotic Thrombocytopenic Purpura (Sarah E. Sartain)....Pages 171-188 Evaluation and Treatment of Thrombotic Thrombocytopenic Purpura (Satheesh Chonat)....Pages 189-203 Front Matter ....Pages 205-205 Background and Pathophysiology of Autoimmune Neutropenia (Jacquelyn M. Powers)....Pages 207-212 Evaluation and Management of Autoimmune Neutropenia (Alicia K. Chang)....Pages 213-221 Back Matter ....Pages 223-230