ENGLISH

Anti-fibrotic drug discovery

By Brenneman , Jehrod; Iyer , Malliga R

Book information

Publisher
Royal­ Society­ of­ Chemistry­
Year
2020
ISBN
9781788015783, 9781788015103, 178801510X
Language
english
Format
PDF
Filesize
13 MB (13517160 bytes)
Series
RSC drug discovery series 73
Pages
xvi, 347 pages: illustrations (color, black and wh
Time added
2020-11-29 04:17:14

Description

Anti-fibrotic Drug Discovery is ideal for postgraduate students and researchers with an interest in anti-fibrotic drug discovery as well as clinicians specialising in liver, kidney, heart and lung disease, in which fibrosis plays a key role in pathology.;TGFß Signalling in Fibrosis; Targeting Integrins in Fibroproliferative Disease; Discovery, Structural Refinement and Therapeutic Potential of Farnesoid X Receptor (FXR) Activators; Autotaxin Inhibitors in Fibrosis; Inhibition of LOXL2 and Other Lysyl Oxidase (Like) Enzymes: Intervention at the Core of Fibrotic Pathology; Galectin-3 Involvement in Fibrotic Diseases; The Emerging Role of CXCR4 in IPF; BH3 Mimetic Drugs for Anti-Fibrotic Therapy; Intratumoral Fibrosis: Emerging Concepts and Therapeutic Opportunities; Targeting Fibroblasts in Cancer and Fibrosis

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