ENGLISH

Three-Dimensional Electron Microscopy of Macromolecular Assemblies Visualization of Biological Mo

By Joachim Frank

Book information

Publisher
Oxford University Press, USA
Year
2006
ISBN
0195182189, 9780195182187, 0195150961, 9780195150964, 9781429415217
LCC
QH324.9.T45 F73 2005
Google Books ID
kjGKy2LeWnUC&am
Open Library ID
OL3295816M
Language
english
Format
PDF
Filesize
10 MB (10287707 bytes)
Edition
2
Pages
428\428
Topic
Biology
Library
Kingdwarf
Orientation
no
Scanned
yes
Time added
2010-01-07 06:59:20

Description

Cryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics and structural biology at present, and Frank is arguably the most distinguished practitioner of this art. CryoEM is likely over the next few years to take over much of the structural approaches currently requiring X-ray crystallography, because one can now get good and finely detailed images of single molecules down to as little as 200,000 MW, covering a substantial share of the molecules of greatest biomedical research interest. This book, the successor to an earlier work published in 1996 with Academic Press, is a natural companion work to our forthcoming book on electron crystallography by Robert Glaeser, with contributions by six others, including Frank. A growing number of workers will employ CryoEM for structural studies in their own research, and a large proportion of biomedical researchers will have a growing interest in understanding what the capabilities and limits of this approach are.

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