Oral anticoagulation therapy: cases and clinical correlation

Description

"This case-based title reviews anticoagulation management strategies available for a wide variety of clinical scenarios. Designed to aid providers of direct patient care on complex clinical decisions regarding appropriate evidence-based therapy options, patient and agent related variables to consider, as well as expert opinion on the topic. Oral Anticoagulation Therapy: Cases and Clinical Correlation will provide clinicians and trainees with clear clinical cases, commentary, and resources to develop their knowledge base, problem-solving skills, and ability to practically apply new knowledge to a variety of clinical situations. Resources provided in cases include valuable figures, tables, and key points designed for the reader to be able to utilize at the point of care."-- Prové de l'editor. Conté: Atrial Fibrillation: Basic simple introductory case -- Patient who desires best reduction in ischemic stroke possible -- Elderly patient (e.g. &gt 80 years old) -- Patient with prior history of GI hemorrhage -- Patient with history of intracranial hemorrhage while on warfarin -- Patient with history of adherence issues who uses pill box -- Patient with stable moderate chronic kidney disease -- Patient with variable renal function -- Patient with concomitant coronary artery disease -- Patient with concomitant history of venous thromboembolism -- Venous Thromboembolism (VTE): Patient with new DVT -- Patient with new PE -- Patient s/p hip replacement -- Patient in ICU in need of DVT prophylaxis -- Patient with VTE and concomitant atherosclerotic disease -- Patient with DVT in ICU with feeding tube -- Patient with moderate chronic kidney disease and VTE -- Patient with recurrent VTE -- Patient with PE who underwent thrombolytic therapy -- Patient s/p knee replacement -- Acute Coronary Syndrome: Patient on a new oral anticoagulant presenting with ACS -- Patient post PCI -- Patient with ACS with additional indication for oral anticoagulant -- Patient with ST segment elevation MI (lytic candidate) on new oral anticoagulant -- Patient with ACS who will be undergoing bypass surgery -- Drug Interactions: CYP 3A4 inhibitors -- PgP inhibitors -- Pharmacodynamic interactions -- Mixed CYP 3A4/PgP inhibitors -- Plausible (but unproven) drug interactions (e.g. cyclosporine) -- Special Populations: Atrial fibrillation ablation -- Mechanical valves -- Coagulopathies -- Pregnancy -- Malignancies -- Perioperative management-minor procedures -- Perioperative management-major procedures.