Genomic Diversity in People of India: Focus on mtDNA and Y-Chromosome polymorphism
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This book is the output of Anthropological Survey of India's National Project "DNA Polymorphism of Contemporary Indian Population" conducted during 2000 to 2018. The book compiles the independent and collaborative work of 49 scientific personnel. Genomics facilitate the study of genetic constitution and diversity at individual and population levels. Genomic diversity explains susceptibility, predisposition and prolongation of diseases; personalized medicine and longevity; prehistoric demographic events, such as population bottleneck, expansion, admixture and natural selection. This book highlights the heterogeneous, genetically diverse population of India. It shows how the central geographic location of India, played a crucial role in historic and pre-historic human migrations, and in peopling different continents of the world. The book describes the massive task undertaken by AnSI to unearth genomic diversity of India populations, with the use of Uni-parental DNA markers mtDNA (mitochondrial DNA) and Y –chromosome in 75 communities. The book talks about the 61 maternal and 35 paternal lineages identified through these studies. It brings forth interesting, hitherto unknown findings such as shared mutations between certain communities. This volume is a milestone in scientific research to understand biological diversity of Indian people at genomic level. It addresses the basic priority to identify different genes underlying various inborn genetic defects and diseases specific to Indian populations. This would be highly interesting to population geneticists, historians, as well as anthropologists. Foreword Contributors Acknowledgement Contents Abbreviations List of Figures List of Tables Chapter 1: Introduction People of India Ethnic and Linguistic Diversity Tribal Populations The Anthropological Survey of India´s Initiative References Chapter 2: Mitochondrial DNA Phylogeny in Indian Population MtDNA M-Macrohaplogroup M-Haplogroups in North East India East Asian M-Haplogroups in India Age Estimates Detailed mtDNA Genotypes and Peopling of Andaman Island Link Between India to Australia References Chapter 3: Mitochondrial DNA Phylogeny of N-Haplogroup in Indian Population Haplogroup U References Chapter 4: mtDNA 9-bp INDEL Polymorphism (np 8272-8280) Among Indian Population References Chapter 5: Population Diversity and Molecular Diversity Indices Based on mtDNA Among Indian Population Macrohaplogroup M Lineages in North-East India Origin of Macrohaplogroup M (Part of the Data Has Been Published in the Article from Elsewhere: Chandrasekar et al. 2009) Migration Routes of Modern Human (Part of the Data Has Been Published in the Article from Elsewhere: Chandrasekar et al. 2009) Evolutionary Antiquity of mtDNA Lineage, M2 Among Indian Populations (Part of the Data Has Been Published in the Article from ... Genetic Link Between Indians and Australian Aborigines Genetic Link Between Indians and Andaman Islands Aborigines (Part of the Data Has Been Published in the Article from Elsewhere... Molecular Diversity Indices References Chapter 6: Y-Chromosome Phylogeny in Indian Population Multi Dimension Analysis for Y-Chromosome SNP YAP (Y-Chromosome Alu Polymorphism) Insertion in Indian Samples (Part of the Data Has Been Published in the Article from Elsew... Evolutionary Implications References Chapter 7: Genomic Diversity of 75 Communities in India Alu Kurumba Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Andh Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Angami Naga Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Betta Kuruba Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Bharia Paternal Lineage (Y Chromosomal Haplogroups) Bhoi Khasi Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Bhoksa Paternal Lineage (Y Chromosomal Haplogroups) Bhotia Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Bondo Paternal Lineage (Y Chromosomal Haplogroups) Chenchu Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Damor Paternal Lineage (Y Chromosomal Haplogroups) Dhodia Paternal Lineage (Y Chromosomal Haplogroups) Dirang Monpa Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Dungri Bhil Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Gadia Lohar Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Galong Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Garwali Brahmin Paternal Lineage (Y Chromosomal Haplogroups) Garhwali Rajput Paternal Lineage (Y Chromosomal Haplogroups) Ghorkha Paternal Lineage (Y Chromosomal Haplogroups) Kolam Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Hmar Paternal Lineage (Y Chromosomal Haplogroups) Irular Paternal Lineage (Y Chromosome Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Jarawa Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Jaunsari Paternal Lineage (Y Chromosomal Haplogroups) Jenu Kuruba Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Ka Thakur Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Kamar Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Kanikkar Paternal Lineage (Y Chromosomal Haplogroups) Karen Paternal Lineage (Y Chromosomal Haplogroups) Kathodi Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Katkari Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Kattunayakan Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Kutia Kondh Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Konda Reddis Paternal Lineage (Y Chromosomal Haplogroups) Koraga Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Korku Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Kota Paternal Lineage (Y Chromosomal Haplogroups) Koya Paternal Lineage (Y Chromosomal Haplogroups) Lachungpa Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Lepcha Paternal Lineage (Y Chromosomal) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Ma Thakur Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Madia Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Mal Paharia Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Mara Paternal Lineage (Y Chromosomal Haplogroups) Mathur Paternal Lineage (Y Chromosomal Haplogroups) Mina Paternal Lineage (Y Chromosomal Haplogroups) Melacheri Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Mizo Paternal Lineage (Y Chromosomal Haplogroups) Mullu Kurumba Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Munda Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Nayaka Paternal Lineage (Y Chromosomal Haplogroups) Nicobarese Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Nihal Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Nishi Paternal Lineage (Y Chromosomal Haplogroups) Padhar Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Paite Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Paniyan Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Pauri Bhuinya Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Porja Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Rabha Paternal Lineage (Y Chromosomal Haplogroups) Raji Paternal Lineage (Y Chromosomal Haplogroups) Saharia Paternal Lineage (Y Chromosomal Haplogroups) Savaras Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Sherdukpen Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Soliga Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Sonowal Kachari Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Tai Ahom Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Tai Khampti Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Tharu Paternal Lineage (Y Chromosomal Haplogroups) Toda Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Toto Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Urali Kuruman Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Wancho Paternal Lineage (Y Chromosomal Haplogroups) Maternal Lineage (mtDNA Haplogroups) Molecular Diversity Yanadi Paternal Lineage (Y Chromosomal Haplogroups) Yerukulas Paternal Lineage (Y Chromosomal Haplogroups) References Index
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