Physiology

Description

This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio­ medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con­ cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as weIl as clinical areas including immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that by presenting information concerning these apparently heterogeneous topics under the unifying umbrella of the RES attention will be focused on the similarities as weIl as interactions among the cell types constitut­ ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol­ umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as weIl as European and Japanese Reticuloendothe­ lial Societies. Front Matter....Pages i-xxiv Front Matter....Pages 1-1 Surface Forces in Phagocytosis....Pages 3-35 Regulation of Mononuclear Phagocyte Proliferation....Pages 37-56 Quantitation of Macrophage Phagocytosis in Vitro ....Pages 57-71 Kinetics of Vascular Clearance of Particles by Phagocytes....Pages 73-101 Vascular Clearance of Microorganisms....Pages 103-113 RES Control of Endotoxemia....Pages 115-143 Front Matter....Pages 145-145 The Reticuloendothelial System and Erythropoiesis....Pages 147-188 Erythroclasia and Bilirubin Metabolism....Pages 189-219 Hemostasis....Pages 221-236 Platelets....Pages 237-266 RES-Leukocyte Interactions....Pages 267-288 Front Matter....Pages 289-289 Glucose Regulation and the RES....Pages 291-303 Interaction of the Reticuloendothelial System with Blood Lipid and Lipoprotein Metabolism....Pages 305-330 Selected Aspects of Protein Metabolism in Relation to Reticuloendothelial System, Lymphocyte, and Fibroblast Function....Pages 331-352 Iron Metabolism....Pages 353-377 Lead and Cadmium Effect on Host Defense Mechanisms and Toxic Interactions with Bacterial Endotoxin....Pages 379-400 Back Matter....Pages 401-411