Bio-Glasses

Description

"Examines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health. Drawing together and analyzing all the latest research findings, this book explores the role of cholesterol in the regulation of ion channels and receptors, including its pathological effects. It is the first book to comprehensively describe the complex mechanisms by which cholesterol regulates two major classes of membrane proteins. Moreover, it sheds new light on how cholesterol affects essential cellular functions such as the contraction of the heart, propagation of nerve impulses, and regulation of blood pressure and kidney function."--;Cholesterol trafficking and distribution between cellular membranes / Daniel Wustner, Lukasz M. Solanko, Frederik W. Lund -- Cholesterol regulation of membrane protein function by changes in bilayer physical properties : an energetic perspective / Jens A. Lundbaek and Olaf S. Andersen -- Insights into structural determinants of cholesterol sensitivity of Kir channels / Avia Rosenhouse-Dantsker and Irena Levitan -- Role for lipid rafts in the regulation of store-operated Ca2+ channels / Hwei L. Ong and Indu S. Ambudkar -- Cholesterol regulation of cardiac ion channels / Elise Balse, Stephane Hatem and Stanley Nattel -- Differential contribution of BK subunits to nongenomic regulation of channel function by steroids / Alex M. Dopico, Anna N. Bukiya, and Aditya K. Singh -- Regulation of K+ channels by cholesterol-rich membrane domains in immune system / Núria Comes and Antonio Felipe -- Indirect channel regulation by cholesterol : the role of caveolae and caveolins in regulating KATP channel function / Caroline Dart -- Regulation of the nicotinic acetylcholine receptor by cholesterol as a boundary lipid / Francisco J. Barrantes -- Specific and non-specific regulation of GPCR function by cholesterol / Gerald Gimpl and Katja Gehrig-Burger -- Structural insights into cholesterol interactions with G protein-coupled receptors / Jeremiah S. Joseph, Enrique E. Abola, and Vadim Cherezov -- Membrane cholesterol : implications in receptor function / Sandeep Shrivastava and Amitabha Chattopadhyay -- The role of cholesterol and lipid rafts in regulation of TLR receptors / Ruxana T. Sadikot. Cholesterol trafficking and distribution between cellular membranes / Daniel Wustner, Lukasz M. Solanko, Frederik W. Lund -- Cholesterol regulation of membrane protein function by changes in bilayer physical properties : an energetic perspective / Jens A. Lundbaek and Olaf S. Andersen -- Insights into structural determinants of cholesterol sensitivity of Kir channels / Avia Rosenhouse-Dantsker and Irena Levitan -- Role for lipid rafts in the regulation of store-operated Ca2+ channels / Hwei L. Ong and Indu S. Ambudkar -- Cholesterol regulation of cardiac ion channels / Elise Balse, Stephane Hatem and Stanley Nattel -- Differential contribution of BK subunits to nongenomic regulation of channel function by steroids / Alex M. Dopico, Anna N. Bukiya, and Aditya K. Singh -- Regulation of K+ channels by cholesterol-rich membrane domains in immune system / Núria Comes and Antonio Felipe -- Indirect channel regulation by cholesterol : the role of caveolae and caveolins in regulating KATP channel function / Caroline Dart -- Regulation of the nicotinic acetylcholine receptor by cholesterol as a boundary lipid / Francisco J. Barrantes -- Specific and non-specific regulation of GPCR function by cholesterol / Gerald Gimpl and Katja Gehrig-Burger -- Structural insights into cholesterol interactions with G protein-coupled receptors / Jeremiah S. Joseph, Enrique E. Abola, and Vadim Cherezov -- Membrane cholesterol : implications in receptor function / Sandeep Shrivastava and Amitabha Chattopadhyay -- The role of cholesterol and lipid rafts in regulation of TLR receptors / Ruxana T. Sadikot.