ENGLISH

DNA Methylation: Approaches, Methods, and Applications

By Esteller , Manel

Book information

Publisher
CRC Press
Year
2004
ISBN
978-0-203-48701-3, 978-0-8493-2050-7, 0-8493-2050-X
DOI
10.1201/9780203487013
Language
english
Format
PDF
Filesize
9 MB (9879994 bytes)
Edition
1
Pages
240\215
Time added
2014-02-12 18:00:00

Description

DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological perspectives on DNA methylation. This is an invaluable handbook for researchers and clinicians interested in genetics and molecular biology, particularly epigenetic therapies and gene silencing

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