ENGLISH

Topics in Fluorescence Spectroscopy: Probe Design and Chemical Sensing

By Joseph R. Lakowicz (eds.) , Joseph R. Lakowicz (auth.)

Book information

Publisher
Springer US
Year
2002
ISBN
0306447843, 9780306447846, 9780306470608
DOI
10.1007/b112911
LCC
QD96.F56 T66 1991
Open Library ID
OL10324695M
Language
english
Format
PDF
Filesize
13 MB (13335499 bytes)
Series
Topics in Fluorescence Spectroscopy 4
Edition
1
Pages
502\520
Topic
Chemistry
Time added
2011-06-04 13:46:07
Biochemistrygeneral; Analytical Chemistry

Description

Time-resolved fluorescence spectroscopy is widely used as a research tool in bioch- istry and biophysics. These uses of fluorescence have resulted in extensive knowledge of the structure and dynamics of biological macromolecules. This information has been gained by studies of phenomena that affect the excited state, such as the local environment, quenching processes, and energy transfer. Topics in Fluorescence Spectroscopy, Volume 4: Probe Design and Chemical Sensing reflects a new trend, which is the use of time-resolved fluorescence in analytical and clinical chemistry. These emerging applications of time-resolved fluorescence are the result of continued advances in laser detector and computer technology. For instance, pho- multiplier tubes (PMT) were previously bulky devices. Miniature PMTs are now available, and the performance of simpler detectors is continually improving. There is also considerable effort to develop fluorophores that can be excited with the red/ne- infrared (NIR) output of laser diodes. Using such probes, one can readily imagine small time-resolved fluorometers, even hand-held devices, being used fordoctor’s office or home health care.

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