Endocrine System

Description

The second edition of this book focuses on the unambiguous identification of lesions in the endocrine system of laboratory animals, a base which is expanded to include new information coming from contemporary techniques, such as invoking mechanisms of action of xenobiotics, identification of cells by their ultrastructure and secretory products, and recognition of effects of toxins on cells and tissues. New methods, applicable to answer a pathologist's questions, are, for example, offered for the study of the hypothalamus and its controlling influence on all endocrine organs. Contemporary concepts of each endocrine organ of laboratory animals and other species are considered and presented in detail, superbly illustrated with gross, histologic, and ultrastructural figures. A basic handbook in toxicologic pathology for the pathologist at the beginning or peak of his or her career, it is also of value to any biologic scientist. Front Matter....Pages I-XVIII Front Matter....Pages 1-1 Functional and Pathologic Interrelationships of the Pituitary Gland and Hypothalamus in Animals....Pages 3-33 Histology, Ultrastructure, and Immunochemistry, Pituitary Gland, Rat....Pages 33-41 Function and Morphology of the Rat Pituitary Gland, Combined Investigations by Means of an In Vitro Model....Pages 42-46 Modern Approaches to Classification of Pituitary Tumors in Human Subjects and Animals....Pages 47-65 Histochemical Identification of Hormones in Pituitary Tumors, Rat....Pages 66-70 Adenoma and Carcinoma, Pars Distalis, Anterior Pituitary Gland, Rat....Pages 71-82 Adenoma, Pars Intermedia, Anterior Pituitary, Rat....Pages 82-86 Craniopharyngioma, Pituitary Gland, Rat....Pages 86-90 Pituitary Tumors Induced by Estrogen, Rat....Pages 90-94 Pituicytoma, Neurohypophysis, Rat....Pages 94-97 Gangliocytoma, Pituitary Gland, Rat....Pages 98-101 Pituitary Gland in the Human Growth-Releasing Factor Transgenic Mouse....Pages 101-105 Cysts, Pituitary, Rat, Mouse, and Hamster....Pages 106-109 Inflammation, Pituitary Gland: Rat, Mouse, and Hamster....Pages 109-110 Cystoid Degeneration Due to Diethylstilbestrol, Anterior Pituitary, Mouse....Pages 110-114 Craniopharyngeal Derivatives in the Neurohypophysis, Rat and Hamster....Pages 114-118 Front Matter....Pages 119-119 Stereotaxic Map, Cytoarchitectonic and Neurochemical Summary of the Hypothalamic Nuclei, Rat....Pages 121-167 Study of Pathologic Lesions in the Hypothalamic-Pituitary System, Rat....Pages 167-178 Hypothalamic-Pituitary Lesions Associated with Diabetes and Aging, Rat....Pages 178-186 Hypothalamic-Pituitary-Adrenal Axis of Genetically Obese fa/fa Rats....Pages 186-190 Front Matter....Pages 191-191 Functional Morphology of the Mammalian Pineal Gland....Pages 193-204 Tumors of the Pineal Gland, Rat....Pages 205-213 Front Matter....Pages 215-215 Hormonal Imbalances and Mechanisms of Chemical Injury of Thyroid Gland....Pages 217-238 Ectopic Thyroid, Mouse....Pages 239-240 Ectopic Thyroid, Rat....Pages 240-241 Ectopic Thymus, Thyroid, Rat....Pages 241-243 Follicular Cell Hyperplasia, Adenoma, and Carcinoma, Thyroid, Rat....Pages 244-254 Adenoma and Carcinoma, Thyroid Follicular Cell, Mouse....Pages 254-261 C-Cell Hyperplasia, C-Cell Adenoma, and C-Cell Carcinoma, Thyroid, Rat....Pages 262-274 Goiter, Nodular Hyperplasia, Adenoma, and Carcinoma of the Thyroid Induced by Amitrole and Ethylenethiourea, Rat....Pages 274-280 Ganglioneuroma, Thyroid Gland, Rat....Pages 280-286 Lymphocytic Thyroiditis, Rat....Pages 287-290 Front Matter....Pages 291-291 Pathobiology of Parathyroid Gland Structure and Function in Animals....Pages 293-325 Anatomy, Histology, and Ultrastructure, Parathyroid, Syrian Hamster....Pages 326-327 Anatomy, Histology, and Ultrastructure, Parathyroid, Mouse....Pages 328-330 Anatomy, Histology, Ultrastructure, Parathyroid, Rat....Pages 330-333 Ectopic Parathyroid, Mouse....Pages 333-334 Hyperplasia, Parathyroid: Syrian Hamster....Pages 335-338 Hyperplasia, Parathyroid, Rat....Pages 338-345 Adenoma, Parathyroid, Syrian Hamster....Pages 345-350 Front Matter....Pages 291-291 Adenoma, Carcinoma, Parathyroid, Rat....Pages 350-358 Front Matter....Pages 359-359 Hyperplasia, Adenoma, and Carcinoma of Pancreatic Islets, Mouse....Pages 361-367 Pancreatic Islet-Cell Hyperplasia, Golden Hamster....Pages 368-371 Adenoma and Carcinoma, Pancreatic Islets, Rat....Pages 371-378 Front Matter....Pages 379-379 Embryology, Adrenal Gland, Mouse....Pages 381-386 Histology, Adrenal Gland, Mouse....Pages 386-391 Accessory Adrenocortical Tissue, Mouse....Pages 391-394 Accessory Adrenocortical Tissue, Rat....Pages 394-396 Immunohistochemical and In Situ Hybridization Analysis of Steroidogenic Enzymes for Study of Steroid Metabolism in Endocrine Organs....Pages 396-404 Cell Proliferation in the Adult Adrenal Medulla: Chromaffin Cells as a Model for Indirect Carcinogenesis....Pages 405-411 Hyperplasia and Pheochromocytoma, Adrenal Medulla, Rat....Pages 411-421 Adrenal Medullary Tumors, Mouse....Pages 421-427 Ganglioneuroma, Adrenal, Rat....Pages 427-432 Neuroblastoma, Adrenal, Rat....Pages 433-435 Focal Hyperplasia, Adrenal Cortex; Rat....Pages 435-439 Adenoma, Adrenal Cortex, Rat....Pages 440-444 Adenocarcinoma, Adrenal Cortex, Rat....Pages 444-448 Adenoma and Carcinoma, Adrenal Cortex, Mouse....Pages 448-454 Amyloidosis, Adrenal, Mouse....Pages 455-458 Lipogenic Pigmentation, Adrenal Cortex, Mouse....Pages 458-462 Front Matter....Pages 379-379 Lipogenic Pigmentation, Adrenal Cortex, Rat....Pages 462-464 Subcapsular-Cell Hyperplasia, Adrenal, Mouse....Pages 464-467 Chemically Induced Adrenocortical Degenerative Lesions....Pages 467-476 Nodular Cortical Hyperplasia, Adrenal, Thymectomized Mouse....Pages 477-481 Lipid Hyperplasia, Adrenal Cortex, Rat....Pages 481-486 Mouse Hepatitis Viral Infection, Adrenal, Mouse....Pages 487-490 Adenovirus Infection, Adrenal, Mouse....Pages 490-493 Murine Cytomegalovirus Infection, Adrenal, Mouse....Pages 494-495 Polyoma Virus Infection, Adrenal, Mouse....Pages 496-498 Lymphocytic Choriomeningitis Virus Infection, Adrenal, Mouse....Pages 499-501 Adrenal Necrosis Due to Besnoitiosis: Golden Hamster....Pages 501-504 Back Matter....Pages 505-523