Polyunsaturated Fatty Acid Metabolism
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Polyunsaturated Fatty Acid Metabolismexplores a number of major roles of PUFA in the body, including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers. Recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic variation on the regulation of PUFA biosynthesis in animals. Together, these recent findings provide novel insights into the impact of differences in PUFA supply on health. This book captures these findings in a manner that marks the state-of-the-art, placing them in the wider context of PUFA metabolism and nutritional science. Users will find a comprehensive discussion on the topic that presents the contributions of leading researchers who combine their knowledge to create a cohesive academic resource for researchers, those involved in production, and health policymakers. Provides a comprehensive view of polyunsaturated fatty acid metabolism Describes underlying metabolism on lipids that include polyunsaturated fatty acids Includes discussions on recent findings on the genetic and epigenetic regulation of polyunsaturated fatty acid metabolism Content: 1. Introduction: more than 50 years of research on polyunsaturated fatty acid metabolism -- 2. Polyunsaturated fatty acid biosynthesis and metabolism in adult mammals -- 3. Polyunsaturated fatty acid biosynthesis and metabolism in fish -- 4. Polyunsaturated fatty acid biosynthesis and metabolism in agriculturally important species -- 5. The biochemistry and regulation of fatty acid desaturases in animals -- 6. Biochemistry and regulation of fatty acid desaturases in animals -- 7. Polyunsaturated fatty acids: metabolism and nutritional requirements in pregnancy and infancy -- 8. Metabolism of polyunstaurated fatty acids by cells of the immune system -- 9. Polyunsaturated fatty biosynthesis and metabolism in reproductive tissues -- 10. The effect of dietary modification on polyunsaturated fatty acid biosynthesis and metabolism -- 11. Omega-3 polyunsaturated fatty acid metabolism in vegetarians -- 12. Genetic influences on polyunsaturated fatty acid biosynthesis and metabolism -- 13. Interactions between plyunsaturated fatty acids and the epigenome -- Index.
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