Barrett’s Esophagus
Book information
Description
Barrett's Esophagus gives an extensive overview written by the world's leading experts covering the epidemiology, gastroenterology and surgery, as well as the molecular basis of: the precursor lesions leading to the development of Barrett's epithelium; the unique characteristics of Barrett's esophagus; the consequences of malignant degeneration, i.e. adenocarcinoma. All aspects in terms of diagnosis, secondary prevention, multimodality, medical and surgical treatment are elucidated. Front Matter....Pages i-xvii Norman Barrett and the Esophagus....Pages 1-15 Anatomy and Embryology of the Esophagus....Pages 17-30 Cell Biology of the Esophageal Epithelium....Pages 31-49 Normal Physiology of the Esophagus....Pages 51-55 Pathophysiology of Gastro-Esophageal Reflux Disease....Pages 57-70 The Natural History of Gastro-Esophageal Reflux Disease....Pages 71-80 Helicobacter Pylori and Reflux Disease....Pages 81-105 Acid and Bile in the Esophagus....Pages 107-120 Endoscopic Classification of Gastro-esophageal Reflux Disease....Pages 121-135 Optimal Surgical Therapy for Anti Reflux Disease....Pages 137-147 Surgical Treatment of Duodeno-Gastro Esophageal Reflux....Pages 149-158 Histopathology of Barrett’s Esophagus....Pages 159-166 The Metaplasia-Dysplasia-Carcinoma Sequence of Barrett’s Esophagus....Pages 167-180 Genetic Alterations....Pages 181-209 Endoscopic Surveillance....Pages 211-216 Short Segment Barrett’s Esophagus and Intestinal Metaplasia at the Gastroesophageal Junction....Pages 217-229 Prevention of Cancer by Control of Reflux....Pages 231-238 Prevention of Cancer in Barrett’s by Ablation....Pages 239-258 The Role of Ablation in the Management of High-Grade Dysplasia....Pages 259-272 Surgical Treatment of High-Grade Dysplasia and Superficial Carcinoma....Pages 273-280 Epidemiology of Barrett’s Esophagus and Adenocarcinoma....Pages 281-290 Adenocarcinoma in Barrett’s Esophagus: Signs, Symptoms and Endoscopic Appearance....Pages 291-295 Adenocarcinoma in Barrett’s Esophagus — Classification and Staging....Pages 297-306 Diagnosis and Implications of Bone Marrow Micrometastases....Pages 307-315 Indications and Outcome of Esophageal Resection....Pages 317-324 Transhiatal Esophagectomy....Pages 325-333 Resection of Esophageal Carcinoma: The Role of Lymph Node Dissection....Pages 335-346 Videoendoscopic Esophagectomy for Cancer....Pages 347-355 Management of Postoperative Complications....Pages 357-366 Multimodality in the Management of Adenocarcinoma of the Esophagus....Pages 367-376 Endoscopic Management of Dysphagia from Esophageal Cancer....Pages 377-386 Function and Quality of Life after Esophageal Resection....Pages 387-392 Back Matter....Pages 393-395
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