Open and Toroidal Electrophoresis: Ultra-High Separation Efficiencies in Capillaries, Microchips and Slabs

Description

Presents the theory and applications of Toroidal Capillary, Microchip, and Slab Electrophoresis to analytical chemists across a range of disciplines   Written by one of the developers of Toroidal Capillary Electrophoresis (TCE), this book is the first to present this novel analytical technique, in detail, to the field of analytical chemistry.   The exact expressions of separation efficiency, resolution, peak capacity, and many other performance indicators of the open and toroidal layouts are presented and compared.   Featuring numerous illustrations throughout, Open and Toroidal Electrophoresis: Ultra-High Separation Efficiencies in Capillaries, Microchips and Slabs offers chapters covering: Solvents and Buffer Solutions; Fundamentals of Electrophoresis; Open Layout; and Toroidal Layout. Confronting Performance Indicators is next, followed by chapters on High Voltage Modules and Distributors; Heat Removal and Temperature Control; and Detectors. The book finishes with an examination of the applications of Toroidal Electrophoresis.   The first book to offer a detailed account of Toroidal Electrophoresis--written by one of its creators * Compares the toroidal layouts with the well-established open layouts of the three most used platforms (Capillary, Microchip, and Slab) * Provides solutions to many of the experimental issues arising in electromigration techniques and discusses the voltage distributors and detectors that are compatible with the toroidal layouts * Richly illustrated with a large number of useful equations showing the relationships between important operational parameters and the performance indicators   Open and Toroidal Electrophoresis is aimed at method developers and separation scientists working in clinical analysis, and food analysis, as well as those in pharmacology, disease biomarker applications, and nucleic acid analysis using the Capillary, Microchip, or slab Platform. It will also benefit undergraduate and graduate students of inorganic analytical chemistry, organic analytical chemistry, bioanalysis, pharmaceutical sciences, clinical sciences, and food analysis. Cover Open and Toroidal Electrophoresis: Ultra-High Separation Efficiencies in Capillaries, Microchips, and Slabs © 2020 Dedication Contents Preface Acronyms Symbols and Conventions Introduction 1 Solvents and Buffer Solutions 2 Fundamentals of Electrophoresis 3 Open Layout 4 Toroidal Layout 5 Confronting Performance Indicators 6 High Voltage Modules and Distributors 7 Heat Removal and Temperature Control 8 Detectors 9 Applications of Toroidal Electrophoresis Appendix A. Nomenclature Appendix B. Species Concentration in Buffer Solutions Appendix C. Electrophoresis Appendix D. Electroosmosis Appendix E. Molecular Diffusion Appendix F. Poiseuille Counter-flow Appendix G. Cyclic On-column Band Compression Index