ENGLISH

The Eukaryotic Replisome: a Guide to Protein Structure and Function

By Stuart MacNeill (auth.) , Stuart MacNeill (eds.)

Book information

Publisher
Springer Netherlands
Year
2012
ISBN
978-94-007-4571-1, 978-94-007-4572-8
DOI
10.1007/978-94-007-4572-8
Language
english
Format
PDF
Filesize
7 MB (7764699 bytes)
Series
Subcellular Biochemistry 62
Edition
1
Pages
348\343
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Biomedicine general; Biochemistrygeneral; Protein Science; Protein Structure; Nucle

Description

High-fidelity chromosomal DNA replication underpins all life on the planet. In humans, there are clear links between chromosome replication defects and genome instability, genetic disease and cancer, making a detailed understanding of the molecular mechanisms of genome duplication vital for future advances in diagnosis and treatment. Building on recent exciting advances in protein structure determination, the book will take the reader on a guided journey through the intricate molecular machinery of eukaryotic chromosome replication and provide an invaluable source of information, ideas and inspiration for all those with an interest in chromosome replication, whether from a basic science, translational biology and medical research perspective.

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