ENGLISH

Protein Folding Handbook

By Johannes Buchner , Thomas Kiefhaber

Book information

Publisher
Wiley-VCH
Year
2005
ISBN
9783527307845, 3527307842, 3527306382, 3527308377, 3527311300, 352730813X, 3527307990
LCC
QH603.R5 P76 2004
Open Library ID
OL17174819M
Language
english
Format
PDF
Filesize
34 MB (35413215 bytes)
Volume
5-volume set
Edition
1
Pages
2590\2590
Topic
Biology
Library
duansci.com
Orientation
no
Scanned
no
Time added
2010-05-17 00:23:50
Биологические дисциплины;Матметоды и моделирование

Description

This unique handbook contains the expertise from more than 60 research groups, covering the entire range of topics in protein folding - from biophysics to molecular medicine. The first part explains the principles and factors governing protein stability, and how this knowledge may be used to predict folding pathways. It also surveys important techniques used to study the protein folding process, including spectroscopic, chemical and biological techniques. The second part is devoted to protein folding, unfolding, and misfolding in the cellular context, introducing chaperones and other enzymes involved in protein folding, as well as a study of the pathophysiology of misfolded proteins in amyloid and other disease states. The whole is rounded off by a discussion of the possibility of interfering with the protein folding process by genetic engineering. The comprehensiveness and outstanding quality of the carefully selected contents make this the ultimate reference for every scientist with an interest in protein folding.

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