Coordination Chemistry in Protein Cages: Principles, Design, and Applications

Description

Featuring contributions from a team of international experts in the coordination chemistry of biological systems, this book enables readers to understand and take advantage of the fascinating internal molecular environment of protein cages. With the aid of modern organic and polymer techniques, the authors explain step by step how to design and construct a variety of protein cages. Moreover, the authors describe current applications of protein cages, setting the foundation for the development of new applications in biology, nanotechnology, synthetic chemistry, and other disciplines. Based on a thorough review of the literature as well as the authors' own laboratory experience, Coordination Chemistry in Protein CagesSets forth the principles of coordination reactions in natural protein cages Details the fundamental design of coordination sites of small artificial metalloproteins as the basis for protein cage design Describes the supramolecular design and assembly of protein cages for or by metal coordination Examines the latest applications of protein cages in biology and nanotechnology Describes the principles of coordination chemistry that govern self-assembly of synthetic cage-like molecules Chapters are filled with detailed figures to help readers understand the complex structure, design, and application of protein cages. Extensive references at the end of each chapter serve as a gateway to important original research studies and reviews in the field. With its detailed review of basic principles, design, and applications, Coordination Chemistry in Protein Cages is recommended for investigators working in biological inorganic chemistry, biological organic chemistry, and nanoscience. Content: Chapter 1 The Chemistry of Nature's Iron Biominerals in Ferritin Protein Nanocages (pages 1–24): Elizabeth C. Theil and Rabindra K. BeheraChapter 2 Molecular Metal Oxides in Protein Cages/Cavities (pages 25–42): Achim Muller and Dieter RehderChapter 3 DE NOVO Design of Protein Cages to Accommodate Metal Cofactors (pages 43–85): Flavia Nastri, Rosa Bruni, Ornella Maglio and Angela LombardiChapter 4 Generation of Functionalized Biomolecules using Hemoprotein Matrices with Small Protein Cavities for Incorporation of Cofactors (pages 87–110): Takashi HayashiChapter 5 Rational Design of Protein Cages for Alternative Enzymatic Functions (pages 111–147): Nicholas M. Marshall, Kyle D. Miner, Tiffany D. Wilson and Yi LuChapter 6 Metal?Directed and Templated Assembly of Protein Superstructures and Cages (pages 149–174): F. Akif TezcanChapter 7 Catalytic Reactions Promoted in Protein Assembly Cages (pages 175–202): Takafumi Ueno and Satoshi AbeChapter 8 Metal?Catalyzed Organic Transformations Inside a Protein Scaffold using Artificial Metalloenzymes (pages 203–219): V. K. K. Praneeth and Thomas R. WardChapter 9 Selective Labeling and Imaging of Protein Using Metal Complex (pages 221–239): Yasutaka Kurishita and Itaru HamachiChapter 10 Molecular Bioengineering of Magnetosomes for Biotechnological Applications (pages 241–271): Atsushi Arakaki, Michiko Nemoto and Tadashi MatsunagaChapter 11 Protein Cage Nanoparticles for Hybrid Inorganic–Organic Materials (pages 273–304): Shefah Qazi, Janice Lucon, Masaki Uchida and Trevor DouglasChapter 12 Nanoparticles Synthesized and Delivered by Protein in the Field of Nanotechnology Applications (pages 305–328): Ichiro Yamashita, Kenji Iwahori, Bin Zheng and Shinya KumagaiChapter 13 Engineered “Cages” for Design of Nanostructured Inorganic Materials (pages 329–349): Patrick B. Dennis, Joseph M. Slocik and Rajesh R. NaikChapter 14 Metal–Organic Caged Assemblies (pages 351–374): Sota Sato and Makoto Fujita