ENGLISH

Affinity Capillary Electrophoresis in Pharmaceutics and Biopharmaceutics

Book information

Publisher
CRC Press
Year
2003
ISBN
0824709519, 9780824709518, 9780824747367
LCC
RS189.5.C34 A345 2003
Language
english
Format
PDF
Filesize
3 MB (3252815 bytes)
Series
Drugs and the Pharmaceutical Sciences: A Series of Textbooks and Monographs
Edition
1
Pages
384\381
Time added
2011-06-04 13:46:07

Description

This reference presents the most recent breakthroughs and techniques in affinity capillary electrophoresis (ACE) to measure and determine the physicochemical and thermodynamic parameters of drug compounds. The authors offer strategies to explore and characterize interactions between drugs, drug vehicles, and biological membranes to facilitate developments in controlled drug delivery and targeting. The book contains current applications and procedures to identify binding constants between drugs, biological structures, proteins, nucleic acids, and plasmids, increase drug bioavailability, enhance the permeability, solubility, strength, and function of drug formulations, examine protein-protein exchanges and reactions, and calculate pKa values.

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