ENGLISH

The Networking of Chaperones by Co-chaperones: Control of Cellular Protein Homeostasis

By Gregory Lloyd Blatch , Adrienne Lesley Edkins (eds.)

Book information

Publisher
Springer International Publishing
Year
2015
ISBN
978-3-319-11730-0, 978-3-319-11731-7
DOI
10.1007/978-3-319-11731-7
Language
english
Format
PDF
Filesize
7 MB (7612232 bytes)
Series
Subcellular Biochemistry 78
Edition
1
Pages
276\286
Time added
2015-02-17 02:00:00
Biomedicine general; Life Sciencesgeneralgeneral; Biochemistry

Description

Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.

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