ENGLISH

Conditional Mutagenesis: An Approach to Disease Models

By R. Feil (auth.) , Professor Dr. Robert Feil , Dr. Daniel Metzger (eds.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2007
ISBN
978-3-540-35108-5, 978-3-540-35109-2
DOI
10.1007/978-3-540-35109-2
Language
english
Format
PDF
Filesize
7 MB (7032731 bytes)
Series
Handbook of Experimental Pharmacology 178
Edition
1
Pages
532\528
Orientation
yes
Scanned
yes
Time added
2013-10-22 02:12:03
Pharmacology/Toxicology; Molecular Medicine; Human

Description

Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2). It illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. Finally the book considers the development of new drugs to treat them.

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