ENGLISH

Cancer Gene Therapy

By David T. Curiel , Joanne T. Douglas

Book information

Publisher
Humana Press
Year
2005
ISBN
1588292134, 1592597858
LCC
RC271.G45 C355 2005
Open Library ID
OL19150786M
Language
english
Format
PDF
Filesize
11 MB (11025043 bytes)
Series
Contemporary cancer research
Edition
1
Pages
502\502
Topic
Medicine Oncology
Library
avaxhome.ws
Time added
2010-05-31 15:29:46

Description

A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation. Topics of special interest include vector-targeting techniques, the lessons learned to date from clinical trials of cancer gene therapy, and the regulatory guidelines for future trials. Noninvasive techniques to monitor the extent of gene transfer and disease regression during the course of treatment are also discussed.

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