ENGLISH

IschemiRs: MicroRNAs in Ischemic Stroke: From Basics to Clinics

By Rajanikant G. K.; Pierre Gressens; Sreekala S. Nampoothiri; Gokul Surendran; Cindy Bokobza

Book information

Publisher
Springer Nature
Year
2020
ISBN
9789811547980, 981154798X
Language
english
Format
EPUB
Filesize
4 MB (4126463 bytes)
Pages
138\0
Time added
2020-06-20 20:49:09

Description

There has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNA’s function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.

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