European Association of Urology Pocket Guidelines 2018

Description

We are pleased to present the 2018 edition of the European Association of Urology (EAU) Guidelines. The EAU Guidelines are the most comprehensive, continuously updated, guidelines available for urologists and related specialties. Produced by a dedicated Guidelines Office, involving approximately 300 international experts drawn from across Europe and beyond, the EAU Guidelines are internationally recognised as an excellent, high-quality, resource for assisting clinicians in their everyday practice. Clinical guidelines are a highly influential tool for improving clinical care, unifying healthcare provision and managing healthcare-associated resources across Europe and beyond. Consequently, they must be transparent, free of bias, give a balanced account of risks and benefits and take into consideration patient preferences. To this end, the 2018 guidelines sees the implementation of a new system for grading guidelines recommendations based upon a modified GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Consequently, each and every recommendation contained within the guidelines, along with the evidence underpinning it, has been reassessed and a Strength Rating Form produced (posted online at: www.uroweb.org/guidelines). Recommendations now take into account the available evidence, the strength and overall quality of that evidence, the balance between desirable and undesirable consequences of any given recommendation compared with alternative interventions, whilst also taking into account patients’ values and preferences. A further change can also be found in the way in which the strength of 2 Introduction each recommendation is represented. Recommendations are no longer denoted by alphabetic characters, but rather by the words ‘strong’ or ‘weak’, with each panel providing both ‘strong’ and ‘weak’ recommendations ‘for’ or ‘against’ a specific intervention. We hope that you find the new format useful and that they provide helpful, clear and unambiguous guidance. Going forward, a key aim of the EAU Guidelines office is to increase patient involvement in Guidelines development. The ultimate aim of this project being the establishment of an effective framework that can ensure that the voices of patients are captured in the development of future guidelines recommendations. The EAU Guidelines Office believes that structured patient engagement will result in recommendations that lead to better treatment compliance and improved health outcomes. This promises to be a challenging but a worthwhile long-term endeavour. The annual publication of the EAU Guidelines would not be possible without the steadfast support of every user of the Guidelines globally, our EAU membership, our greatly respected Guidelines Panels, Guidelines Associates, the EAU Executive Committee and Management team and, last but not least, the National Societies. So, on behalf of the EAU Guidelines Office Board, thank you for your support and inspiration. We hope you find the 2018 update of the EAU Guidelines a pleasure to use! Prof. James N’Dow Chairman EAU Guidelines Office Page 9 Non-muscle Invasive Bladder Cancer Page 27 Urothelial Carcinoma of the Upper Urinary Tract Page 37 Muscle-invasive and Metastatic Bladder Cancer Page 53 Prostate Cancer Page 79 Renal Cell Carcinoma Page 101 Testicular Cancer Page 120 Penile Cancer Page 135 Non-neurogenic Male LUTS, incl. benign prostatic obstruction (BPO) Page 155 Urinary Incontinence Page 179 Neuro-Urology Page 192 Male Sexual Dysfunction: Erectile Dysfunction and Premature Ejaculation Page 208 Priapism Page 217 Penile Curvature Page 225 Male Infertility Page 242 Male Hypogonadism Page 253 Urological Infections Page 273 Urolithiasis Page 306 Paediatric Urology Page 338 Urological Trauma Page 355 Chronic Pelvic Pain Page 378 Renal Transplantation Page 398 Thromboprophylaxis in Urological Surgery