ENGLISH

Steroid Hormones and the T-Cell Cytokine Profile

By Robert Dantzer , Sophie Layé (auth.) , Professor G. A. W. Rook , Professor S. Lightman (eds.)

Book information

Publisher
Springer-Verlag London
Year
1997
ISBN
978-1-4471-1238-9, 978-1-4471-0931-0
DOI
10.1007/978-1-4471-0931-0
Language
english
Format
PDF
Filesize
13 MB (13600111 bytes)
Edition
1
Pages
227\232
Time added
2013-12-12 02:00:00
Immunology; Endocrinology; Human Physiology

Description

The fact that certain adrenal steroid hormones are immunosuppresive and anti-inflammatory has been known for many years. However, new information has led to the possibility of immunoregulatory steroids being used by physicians in novel ways. This book details these new therapies which could revolutionise the treatment of certain Th2-mediated diseases such as asthma. It provides an overview of these new concepts, starting with how the immune response triggers adrenal steroid production and finishing with in vivo models of infection and autoimmunity that demonstrate the clinical importance of these new insights into the physiological control of glucocorticoid function. The information contained is mostly very new, some of it previously unpublished, and will open up new horizons for immunologists, endocrinologists, physiologists, cell biologists and clinicians.

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