ENGLISH

Cancer clinical trials: current and controversial issues in design and analysis

By Stephen L. George , Xiaofei Wang , Herbert Pang

Book information

Publisher
Chapman and Hall/CRC
Year
2016
ISBN
1498706886, 978-1-4987-0688-9, 9781498706902, 1498706908
DOI
10.1186/1741
Language
english
Format
EPUB
Filesize
8 MB (8426843 bytes)
Series
Chapman & Hall/CRC biostatistics series
Pages
474\0
Time added
2016-12-28 23:28:40
Clinical trials;Statistical methods;Cancer;Researc

Description

Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. Well-known statisticians from academic institutions, regulatory and government agencies (such as the U.S. FDA and National Cancer Institute), and the pharmaceutical industry share their extensive experiences in cancer clinical trials and present examples taken from actual trials. The book covers topics that are often perplexing and sometimes controversial in cancer clinical trials. Most of the issues addressed are also important for clinical trials in other settings. After discussing general topics, the book focuses on aspects of early and late phase clinical trials. It also explores personalized medicine, including biomarker-based clinical trials, adaptive clinical trial designs, and dynamic treatment regimes.

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