Nuclear Medicine Therapy: Side Effects and Complications

Description

This book considers how Nuclear Medicine treatments have been further developed in the past several years and are now widely applied in clinical practice, especially in oncological patients, in addition to radioiodine therapy for various thyroid diseases. These treatments are very effective when properly indicated, but side effects and complications specifically related to the radioactive drugs and other potential clinical problems should also be considered, since other treatments, e.g. chemotherapy or radiotherapy, are frequently administered before, simultaneously with and/or after radionuclide therapies. Consequently, cumulative toxicities and treatment interactions must be considered, and physicians prescribing treatments should be capable of preventing (when possible) and properly diagnosing and treating such side effects and complications. Accordingly, expertise in radionuclide therapy and extensive clinical expertise are required to appropriately manage critical cases. This book provides essential information on the physiopathology and radiopharmacy of radionuclide treatments and addresses potential side effects and complications by providing a rapid consultation guide for clinicians: synopses, diagnostic flow-charts and treatment schedules for a range of nuclear medicine treatments Front Matter ....Pages i-ix Nuclear Medicine Theranostics: Between Atoms and Patients (Alice Lorenzoni, Antonella Capozza, Ettore Seregni, Luca Giovanella)....Pages 1-9 Radioiodine Therapy of Benign Thyroid Diseases (Alfredo Campennì, Desiree Deandreis, Monica Finessi, Rosaria Maddalena Ruggeri, Sergio Baldari)....Pages 11-33 Radioiodine Therapy of Thyroid Cancer (Frederik A. Verburg)....Pages 35-42 Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors (Flavio Forrer)....Pages 43-64 131I-MIBG Therapy of Malignant Neuroblastoma and Pheochromocytoma (Arnoldo Piccardo, Luca Foppiani, Sergio Righi, Alberto Garaventa, Stefania Sorrentino, Egesta Lopci)....Pages 65-83 Radiometabolic Therapy of Bone Metastases (Gaetano Paone, Egbert U. Nitzsche)....Pages 85-99 Selective Internal Radiotherapy (SIRT) of Primary Hepatic Carcinoma and Liver Metastases (Niklaus Schaefer)....Pages 101-112 Radioimmunotherapy of Lymphomas (Clément Bailly, Caroline Bodet-Milin, François Guerard, Nicolas Chouin, Joelle Gaschet, Michel Cherel et al.)....Pages 113-121