ENGLISH

Nano-Bio Probe Design and Its Application for Biochemical Analysis

By Min Zhang , Bang-Ce Ye , Bin-Cheng Yin (auth.)

Book information

Publisher
Springer-Verlag Berlin Heidelberg
Year
2012
ISBN
978-3-642-29542-3, 978-3-642-29543-0
DOI
10.1007/978-3-642-29543-0
Language
english
Format
PDF
Filesize
2 MB (2441763 bytes)
Series
SpringerBriefs in Molecular Science
Edition
1
Pages
77\82
Orientation
yes
Scanned
yes
Time added
2013-08-01 04:00:00
Biochemical Engineering;Nanotechnology;Biochemistrgeneral;Nanoscale Science and Technology

Description

In this volume, Prof. Ye and his coworkers propose and review the concept of nano-bio probe design for biochemical analysis on the basis of their recent published works. A unique biochemical analysis technology based on fluorescence polarization enhanced by nanoparticles is described here with successful applications in environmental monitoring, rapid and sensitive sensing protease activity and high-throughput screening of inhibitors. Furthermore, they introduce a versatile molecular beacon (MB)-like probe for the multiplex sensing of targets such as sequence-specific DNA, protein, metal ions and small molecule compounds based on the self-assembled biomolecule-graphene conjugates. Besides, some colorimetric and luminescence probes utilizing metal nanoparticles for biochemical applications are also presented, such as chiral enantiomer discrimination and separation, environmental monitoring, clinic diagnosis and etc.

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