ENGLISH

Fungal Physiology and Immunopathogenesis

By Marcio L. Rodrigues

Book information

Publisher
Springer International Publishing
Year
2019
ISBN
978-3-030-30236-8, 978-3-030-30237-5
Language
english
Format
PDF
Filesize
5 MB (5642107 bytes)
Series
Current Topics in Microbiology and Immunology 422
Edition
1st ed. 2019
Pages
VIII, 301\304
Time added
2020-02-08 04:41:50
Biomedicine; Immunology; Medical Microbiology; Pha

Description

This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light. In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the book’s closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine. Front Matter ....Pages i-viii The Role of Melanin in Fungal Pathogenesis for Animal Hosts (Daniel F. Q. Smith, Arturo Casadevall)....Pages 1-30 The Overlooked Glycan Components of the Cryptococcus Capsule (Fernanda L. Fonseca, Flavia C. G. Reis, Bianca A. G. Sena, Luísa J. Jozefowicz, Livia Kmetzsch, Marcio L. Rodrigues)....Pages 31-43 Extracellular Vesicles in Fungi: Composition and Functions (Sharon de Toledo Martins, Paulo Szwarc, Samuel Goldenberg, Lysangela Ronalte Alves)....Pages 45-59 From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis (Virginia Basso, Christophe d’Enfert, Sadri Znaidi, Sophie Bachellier-Bassi)....Pages 61-99 Cryptococcal Titan Cells: When Yeast Cells Are All Grown up (Rocío García-Rodas, HC de Oliveira, Nuria Trevijano-Contador, Oscar Zaragoza)....Pages 101-120 The Clock Keeps on Ticking: Emerging Roles for Circadian Regulation in the Control of Fungal Physiology and Pathogenesis (Luis F. Larrondo, Paulo Canessa)....Pages 121-156 Histoplasma Capsulatum: Mechanisms for Pathogenesis (Jamie Mittal, Maria G. Ponce, Inessa Gendlina, Joshua D. Nosanchuk)....Pages 157-191 Transcriptome Sequencing Approaches to Elucidate Host–Microbe Interactions in Opportunistic Human Fungal Pathogens (Hrant Hovhannisyan, Toni Gabaldón)....Pages 193-235 Host Genetic Signatures of Susceptibility to Fungal Disease (Cláudia F. Campos, Frank L. van de Veerdonk, Samuel M. Gonçalves, Cristina Cunha, Mihai G. Netea, Agostinho Carvalho)....Pages 237-263 Fungi as Part of the Microbiota and Interactions with Intestinal Bacteria (Mario Kapitan, M. Joanna Niemiec, Alexander Steimle, Julia S. Frick, Ilse D. Jacobsen)....Pages 265-301

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