ENGLISH

Coordinating Organismal Physiology Through the Unfolded Protein Response

By R. Luke Wiseman , Cole M. Haynes

Book information

Publisher
Springer International Publishing
Year
2018
ISBN
978-3-319-78529-5, 978-3-319-78530-1
Language
english
Format
PDF
Filesize
5 MB (5041766 bytes)
Series
Current Topics in Microbiology and Immunology 414
Edition
1st ed.
Pages
VII, 213\218
Time added
2018-08-15 07:07:45
Biomedicine; Immunology; Human Physiology; Neurosc

Description

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike. Front Matter ....Pages i-vii Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response (Madeline Y. Wong, Andrew S. DiChiara, Patreece H. Suen, Kenny Chen, Ngoc-Duc Doan, Matthew D. Shoulders)....Pages 1-25 Cell Non-autonomous UPRER Signaling (Soudabeh Imanikia, Ming Sheng, Rebecca C. Taylor)....Pages 27-43 The Unfolded Protein Response in the Immune Cell Development: Putting the Caretaker in the Driving Seat (Simon J. Tavernier, Bart N. Lambrecht, Sophie Janssens)....Pages 45-72 Mitochondria-Associated Membranes and ER Stress (Alexander R. van Vliet, Patrizia Agostinis)....Pages 73-102 Coordinating Organismal Metabolism During Protein Misfolding in the ER Through the Unfolded Protein Response (Vishwanatha K. Chandrahas, Jaeseok Han, Randal J. Kaufman)....Pages 103-130 ER Stress and Neurodegenerative Disease: A Cause or Effect Relationship? (Felipe Cabral-Miranda, Claudio Hetz)....Pages 131-157 Driving Cancer Tumorigenesis and Metastasis Through UPR Signaling (Alexandra Papaioannou, Eric Chevet)....Pages 159-192 ER Protein Quality Control and the Unfolded Protein Response in the Heart (A. Arrieta, E. A. Blackwood, C. C. Glembotski)....Pages 193-213

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